Personal profile
Teaching Experience
BIOB 410 - Immunology
BIOB 411 - Immunology Lab
MICB 502 - Advanced Immunology
BIOB 596 - Principles of Light Microscopy
Research Interests
Work in my lab focuses on CD4+ T lymphocyte activation and subset differentiation.
We have 2 basic Research Areas:
1. The biological consequences for individual T cells of signaling induced by APC-derived membrane molecules after their transfer to T cells at the T-APC immunological synapse, a process termed “trogocytosis”.
2. The impact of the herbicide Atrazine on the activation of CD4+ T cells and the mechanism underlying a significant increase in Foxp3+ regulatory T cells
Education/Academic qualification
Master, California State Polytechnic University Pomona
PhD, Immunology, Oregon Health and Science University
Bachelor, University of La Verne
Free-text Keywords
- cellular immunology
- immunotoxicology
- Trogocytosis-Mediated Signaling
- CD4+ T Cell Subset Differentiation
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
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The Biological Significance of Trogocytosis
Agbakwuru, D. & Wetzel, S. A., 2024, Results and Problems in Cell Differentiation. Springer Science and Business Media Deutschland GmbH, Vol. 73. p. 87-129 43 p. (Results and problems in cell differentiation).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
3 Scopus citations -
Lymphocytes and trogocytosis-mediated signaling
Reed, J., Reichelt, M. & Wetzel, S. A., Jun 2021, In: Cells. 10, 6, 1478.Research output: Contribution to journal › Review article › peer-review
Open Access33 Scopus citations -
Assessing in vitro and in vivo Trogocytosis By Murine CD4+ T cells
Reed, J. & Wetzel, S. A., May 5 2020, In: Bio-protocol. 10, 9, e3607.Research output: Contribution to journal › Article › peer-review
Open Access -
Trogocytosis-mediated intracellular signaling in CD4+ T cells drives Th2-associated effector cytokine production and differentiation
Reed, J. & Wetzel, S. A., May 15 2019, In: Journal of Immunology. 202, 10, p. 2873-2887 15 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
CD4 + T cell differentiation and activation
Reed, J. & Wetzel, S. A., 2018, Methods in Molecular Biology. Humana Press Inc., p. 335-351 17 p. (Methods in Molecular Biology; vol. 1803).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Open Access7 Scopus citations