TY - JOUR
T1 - A bacterial-induced lectin which triggers hemocyte coagulation in Manduca sexta
AU - Minnick, M. F.
AU - Rupp, R. A.
AU - Spence, K. D.
PY - 1986/6/13
Y1 - 1986/6/13
N2 - An inducible hemagglutinin termed M13, was purified from M. sexta hemolymph. M13 is a glucose-specific lectin which in addition to erythrocyte agglutination, can activate dedifferentiation of various hemocytes into a filamentous coagulation network. When lectin activity was inhibited with glucose or antiserum, neither erythrocyte agglutination or hemocyte coagulation occurred. When M13 was boiled or trypsin treated, hemocyte activation was lost, but erythrocyte agglutination remained. Hence M13 activity appears to be bimodal, possessing both a lectin activity and a hemocyte-coagulating activity.
AB - An inducible hemagglutinin termed M13, was purified from M. sexta hemolymph. M13 is a glucose-specific lectin which in addition to erythrocyte agglutination, can activate dedifferentiation of various hemocytes into a filamentous coagulation network. When lectin activity was inhibited with glucose or antiserum, neither erythrocyte agglutination or hemocyte coagulation occurred. When M13 was boiled or trypsin treated, hemocyte activation was lost, but erythrocyte agglutination remained. Hence M13 activity appears to be bimodal, possessing both a lectin activity and a hemocyte-coagulating activity.
UR - http://www.scopus.com/inward/record.url?scp=0023047954&partnerID=8YFLogxK
U2 - 10.1016/0006-291X(86)91139-3
DO - 10.1016/0006-291X(86)91139-3
M3 - Article
C2 - 3524562
AN - SCOPUS:0023047954
SN - 0006-291X
VL - 137
SP - 729
EP - 735
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -