A comparative study of database reduction methods for case-based computer-aided detection systems: Preliminary results

Maciej A. Mazurowski, Jordan M. Malof, Jacek M. Zurada, Georgia D. Tourassi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations


In case-based computer-aided decision systems (CB-CAD) a query case is compared to known examples stored in the systems case base (also called a reference library). These systems offer competitive classification performance and are easy to expand. However, they also require efficient management of the case base. As CB-CAD systems are becoming more popular, the problem of case base optimization has recently attracted interest among CAD researchers. In this paper we present preliminary results of a study comparing several case base reduction techniques. We implemented six techniques previously proposed in machine learning literature and applied it to the classification problem of distinguishing masses and normal tissue in mammographic regions of interest. The results show that the random mutation hill climbing technique offers a drastic reduction of the number of case base examples while providing a significant improvement in classification performance. Random selection allowed for reduction of the case base to 30% without notable decrease in performance. The remaining techniques (i.e., condensed nearest neighbor, reduced nearest neighbor, edited nearest neighbor, and All k-NN) resulted in moderate reduction (to 50-70% of the original size) at the cost of decrease in CB-CAD performance.

Original languageEnglish
Title of host publicationMedical Imaging 2009
Subtitle of host publicationComputer-Aided Diagnosis
StatePublished - 2009
EventMedical Imaging 2009: Computer-Aided Diagnosis - Lake Buena Vista, FL, United States
Duration: Feb 10 2009Feb 12 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMedical Imaging 2009: Computer-Aided Diagnosis
Country/TerritoryUnited States
CityLake Buena Vista, FL


  • Classification and classifier design
  • Database construction
  • Detection
  • Mammography


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