A Novel Sulfate Polymer as a Pseudo-Stationary Phase for Micellar Electrokinetic Chromatography

A stable monomolecular pseudo-stationary phase for use in micellar electrokinetic chromatography has been synthesized and evaluated. Sodium 10- undecenyl sulfate has been synthesized and polymerized to form a micelle-like structure following a procedure similar to that previously employed for sodium 10-undecylenate. As with other high molecular surfactants, the effective critical micelle concentration of this pseudo-stationary phase is zero. Covalent stabilization of the micelle does not adversely affect the efficiency of the separations. The new phase has higher electrophoretic mobility than micelles of sodium dodecyl sulfate, thus providing a wider elution range. The stability of the new phase permits its use with relatively high percentages of organic modifiers in the mobile phase, allowing the separation of hydrophobic solutes.