A unique group I intron in Coxiella burnetii is a natural splice mutant

Rahul Raghavan; Linda D. Hicks; Michael F. Minnick

doi:10.1128/JB.00359-09

A unique group I intron in Coxiella burnetii is a natural splice mutant

Rahul Raghavan, Linda D. Hicks, Michael F. Minnick

Biological Sciences

University of Montana

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Cbu.L1917, a group I intron present in the 23S rRNA gene of Coxiella burnetii, possesses a unique 3′-terminal adenine in place of a conserved guanine. Here, we show that, unlike all other group I introns, Cbu.L1917 utilizes a different cofactor for each splicing step and has a decreased self-splicing rate in vitro.

Original language	English
Pages (from-to)	4044-4046
Number of pages	3
Journal	Journal of Bacteriology
Volume	191
Issue number	12
DOIs	https://doi.org/10.1128/JB.00359-09
State	Published - Jun 2009

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title = "A unique group I intron in Coxiella burnetii is a natural splice mutant",

abstract = "Cbu.L1917, a group I intron present in the 23S rRNA gene of Coxiella burnetii, possesses a unique 3′-terminal adenine in place of a conserved guanine. Here, we show that, unlike all other group I introns, Cbu.L1917 utilizes a different cofactor for each splicing step and has a decreased self-splicing rate in vitro.",

author = "Rahul Raghavan and Hicks, {Linda D.} and Minnick, {Michael F.}",

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AU - Raghavan, Rahul

AU - Hicks, Linda D.

AU - Minnick, Michael F.

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N2 - Cbu.L1917, a group I intron present in the 23S rRNA gene of Coxiella burnetii, possesses a unique 3′-terminal adenine in place of a conserved guanine. Here, we show that, unlike all other group I introns, Cbu.L1917 utilizes a different cofactor for each splicing step and has a decreased self-splicing rate in vitro.

AB - Cbu.L1917, a group I intron present in the 23S rRNA gene of Coxiella burnetii, possesses a unique 3′-terminal adenine in place of a conserved guanine. Here, we show that, unlike all other group I introns, Cbu.L1917 utilizes a different cofactor for each splicing step and has a decreased self-splicing rate in vitro.

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DO - 10.1128/JB.00359-09

M3 - Article

C2 - 19376857

AN - SCOPUS:67549140425

SN - 0021-9193

VL - 191

SP - 4044

EP - 4046

JO - Journal of Bacteriology

JF - Journal of Bacteriology

IS - 12

ER -

A unique group I intron in Coxiella burnetii is a natural splice mutant

Abstract

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