A unique group I intron in Coxiella burnetii is a natural splice mutant

Rahul Raghavan, Linda D. Hicks, Michael F. Minnick

Research output: Contribution to journalArticlepeer-review

Abstract

Cbu.L1917, a group I intron present in the 23S rRNA gene of Coxiella burnetii, possesses a unique 3′-terminal adenine in place of a conserved guanine. Here, we show that, unlike all other group I introns, Cbu.L1917 utilizes a different cofactor for each splicing step and has a decreased self-splicing rate in vitro.

Original languageEnglish
Pages (from-to)4044-4046
Number of pages3
JournalJournal of Bacteriology
Volume191
Issue number12
DOIs
StatePublished - Jun 2009

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