Acanthosis Nigricans among Northern Plains American Indian children

Blakely Brown, Curtis Noonan, Bonnie Bentley, Kathrene Conway, Mary Corcoran, Kris FourStar, Shannon Gress, Sharon Wagner

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The purpose of this study is to present cross-sectional and prospective data on acanthosis nigricans (AN) prevalence in the context of other risk factors for diabetes including high body mass index (BMI), abnormal blood pressure (BP), physical inactivity and family history of diabetes among Northern Plains American Indian (AI) children. Standardized health measures were collected in 2,520 K-12th-grade AI students for AN, BMI, and BP. Data were also collected on family history of diabetes and physical activity. Approximately, 9.7% of the participants were positive for AN. AN was associated with high BMI, abnormal BP, and diabetes family history. Sports participation was inversely associated with AN. Among children measured the prior year, relative risk (and 95% confidence interval [CI]) for obesity and incident AN was 9.8 (4.2-23.0) compared to normal weight. These findings suggest there is utility in measuring this marker of insulin resistance in this at-risk population.

Original languageEnglish
Pages (from-to)450-460
Number of pages11
JournalJournal of School Nursing
Issue number6
StatePublished - Dec 2010


  • diabetes
  • elementary
  • middle/junior/high school
  • obesity
  • screening/risk identification


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