Aerobic exercise training versus the aetiology of insulin resistance

Type 2 diabetes represents an epidemic disease that has become a widespread healthcare problem throughout the world. The prevalence of a sedentary lifestyle and excess caloric intake promotes the aetiology of insulin resistance that results in the development of the metabolic condition, Type 2 diabetes. Despite numerous investigations that have demonstrated the positive influence of aerobic exercise training on a reduction in the severity of insulin resistance, many of these exercise programmes yield benefits that are only short-lived and promote only modest reductions in the severity of the disease aetiology. Therefore, the efficacy of exercise training as a therapeutic intervention against the development of Type 2 diabetes rests on its ability to normalize insulin resistance in the liver and skeletal muscle using a progressive approach that combines the beneficial influences of exercise training and weight loss.