Bacteriophages of Spirochetes

Christian H. Eggers, Sherwood Casjens, Stanley F. Hayes, Claude F. Garon, Christopher J. Damman, Donald B. Oliver, D. Scott Samuels

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Historically, a number of bacteriophage-like particles have been observed in association with members of the bacterial order Spirochetales, the spirochetes. In the last decade, several spirochete bacteriophages have been isolated and characterized at the molecular level. We have recently characterized a bacteriophage of the Lyme disease agent, Borrelia burgdorferi, which we have designated φBB-1. Here we review the history of the association between the spirochetes and their bacteriophages, with a particular emphasis on φBB-1 and its prophage, the 32-kb circular plasmid family of B. burgdorferi.

Original languageEnglish
Pages (from-to)365-373
Number of pages9
JournalJournal of Molecular Microbiology and Biotechnology
Issue number4
StatePublished - 2000


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