Bioactive secondary metabolites produced by the fungal endophytes of conifers

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Abstract

This is a review of bioactive secondary metabolites isolated from conifer-associated endophytic fungi from 1990-2014. This includes compounds with antimicrobial, anti-inflammatory, anti-proliferative and cytotoxic activity towards human cancer cell lines, and activity against either plant pathogens or plant insect pests. Compounds that were originally reported without associated activity were included if other studies ascribed activity to these compounds. Compounds were not included if they were exclusively phytotoxic or if they were isolated from active extracts but were not determined to be the active component of that extract.

Original languageEnglish
Pages (from-to)1671-1682
Number of pages12
JournalNatural Product Communications
Volume10
Issue number10
DOIs
StatePublished - Oct 2015

Keywords

  • Bioactivity
  • Conifer
  • Cypress
  • Endophyte
  • Endophytic fungus
  • Natural products
  • Pine
  • Secondary metabolites
  • Spruce

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