@article{24d35287afcb414f99adbb7eafc7b38c,
title = "Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity",
abstract = "Dimeric analogs of Anthracenyl Isoxazole Amides (AIMs) (the designation AIM is in honor of the memory of Professor Albert I. Meyers) were prepared and dimer 6 exhibited the highest efficacy to date for this class of anti-tumor compounds against the human glioma Central Nervous System cell line SNB-19.",
keywords = "Anthracene, Antitumor, Fluorescence, G-quadruplex DNA, Glioma, Isoxazole, SNB-19",
author = "Gajewski, {Mariusz P.} and Howard Beall and Mark Schnieder and Stranahan, {Sarah M.} and Mosher, {Michael D.} and Rider, {Kevin C.} and Natale, {Nicholas R.}",
note = "Funding Information: The authors are grateful to the National Institutes of Health for NINDS 7R15-NS038444-04 and P20 RR015583. We thank Dr. J. B. A. (Sandy) Ross, director of the BioSpectroscopy Core at the Center for Structural and Functional Neuroscience, University of Montana, and Ayesha Sharmin for their assistance with fluorescence spectroscopy, funded by P20 RR015583. S.M.S. acknowledges summer research support from NSF REU CHE 0243760, while N.R.N. was at the University of Idaho. K.C.R. thanks P30 NS055022. We would like to thank Dr. Keith Taylor for helpful discussions on the implementation of Symyx Draw. We thank ChemAxon for use of their software. We also acknowledge Dr. David J. Burkhart of GSKBio for the use of their NMR. ",
year = "2009",
month = aug,
day = "1",
doi = "10.1016/j.bmcl.2009.06.019",
language = "English",
volume = "19",
pages = "4067--4069",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Ltd",
number = "15",
}