Bis-anthracenyl isoxazolyl amides have enhanced anticancer activity

Mariusz P. Gajewski, Howard Beall, Mark Schnieder, Sarah M. Stranahan, Michael D. Mosher, Kevin C. Rider, Nicholas R. Natale

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Dimeric analogs of Anthracenyl Isoxazole Amides (AIMs) (the designation AIM is in honor of the memory of Professor Albert I. Meyers) were prepared and dimer 6 exhibited the highest efficacy to date for this class of anti-tumor compounds against the human glioma Central Nervous System cell line SNB-19.

Original languageEnglish
Pages (from-to)4067-4069
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Issue number15
StatePublished - Aug 1 2009


  • Anthracene
  • Antitumor
  • Fluorescence
  • G-quadruplex DNA
  • Glioma
  • Isoxazole
  • SNB-19


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