Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.

M. P. Kavanaugh; H. Wang; C. A. Boyd; R. A. North; D. Kabat

doi:10.1007/978-3-7091-9326-6_47

Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.

M. P. Kavanaugh, H. Wang, C. A. Boyd, R. A. North, D. Kabat

Oregon Health and Science University

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.

Original language	English
Pages (from-to)	485-494
Number of pages	10
Journal	Archives of virology. Supplementum
Volume	9
DOIs	https://doi.org/10.1007/978-3-7091-9326-6_47
State	Published - 1994

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title = "Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.",

abstract = "The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.",

author = "Kavanaugh, {M. P.} and H. Wang and Boyd, {C. A.} and North, {R. A.} and D. Kabat",

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T2 - a cationic amino acid transporter.

AU - Kavanaugh, M. P.

AU - Wang, H.

AU - Boyd, C. A.

AU - North, R. A.

AU - Kabat, D.

PY - 1994

Y1 - 1994

N2 - The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.

AB - The cell surface receptor for ecotropic host-range murine leukemia viruses is a sodium-independent transporter for essential cationic acids. Our evidence strongly identifies this receptor as the transporter system y+, which was previously characterized by transport assays. Mutational analysis indicates that transporter activity is not necessary for viral reception. Infection of cells with ecotropic retroviruses causes only a partial down-modulation of receptor expression on cell surfaces.

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U2 - 10.1007/978-3-7091-9326-6_47

DO - 10.1007/978-3-7091-9326-6_47

M3 - Review article

C2 - 8032277

AN - SCOPUS:0028309203

SN - 0939-1983

VL - 9

SP - 485

EP - 494

JO - Archives of virology. Supplementum

JF - Archives of virology. Supplementum

ER -

Cell surface receptor for ecotropic host-range mouse retroviruses: a cationic amino acid transporter.

Abstract

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