A ribosomal RNA operon was cloned from the agent of human Oroya fever, Bartonella bacilliformis. The 3′ end of the operon contains a 77-nucleotide (nt) N-formylmethionine (fMet) initiator tRNA-encoding gene with 100% sequence identity to the fMet tRNA-encoding gene of Rhodobacter sphaeroides. The 3′ region downstream from the gene has an 8-nt inverted repeat and 28 contiguous direct repeats of the heptamer 5′-TTCTCTA. To date, B. bacilliformis and R. sphaeroides are the only known eubacteria which have an fMet tRNA-encoding gene within the 3′ end of their rRNA operons.
- hemotrophic pathogenic bacteria
- nucleotide sequence
- Oroya fever
- Rhodobacter, Rickettsiales
- ribosomal RNA operon