TY - JOUR
T1 - Different selective pressures lead to different genomic outcomes as newly-formed hybrid yeasts evolve
AU - Piotrowski, Jeff S.
AU - Nagarajan, Saisubramanian
AU - Kroll, Evgueny
AU - Stanbery, Alison
AU - Chiotti, Kami E.
AU - Kruckeberg, Arthur L.
AU - Dunn, Barbara
AU - Sherlock, Gavin
AU - Rosenzweig, Frank
N1 - Funding Information:
The authors wish to thank Carla Boulianne-Larsen and Jeff Good for critically reading the manuscript. Gregory Koniges performed heat shock experiments to distinguish between induced and inherent thermal resistance. Flow cytometry was performed with the assistance of Pamela Shaw. We thank Minoru Yoshida and Astellas Pharma for the use of Micafungin. This work was supported by grants to GS from Global Climate and Energy Project (Grant #33450) and to FR from NASA NNX07AJ28G, as well as by NIH grant P20RR017670 to the University of Montana Fluorescence Cytometry Core Facility.
PY - 2012
Y1 - 2012
N2 - Interspecific hybridization occurs in every eukaryotic kingdom. While hybrid progeny are frequently at a selective disadvantage, in some instances their increased genome size and complexity may result in greater stress resistance than their ancestors, which can be adaptively advantageous at the edges of their ancestors' ranges. While this phenomenon has been repeatedly documented in the field, the response of hybrid populations to long-term selection has not often been explored in the lab. To fill this knowledge gap we crossed the two most distantly related members of the Saccharomyces sensu stricto group, S. cerevisiae and S. uvarum, and established a mixed population of homoploid and aneuploid hybrids to study how different types of selection impact hybrid genome structure.
AB - Interspecific hybridization occurs in every eukaryotic kingdom. While hybrid progeny are frequently at a selective disadvantage, in some instances their increased genome size and complexity may result in greater stress resistance than their ancestors, which can be adaptively advantageous at the edges of their ancestors' ranges. While this phenomenon has been repeatedly documented in the field, the response of hybrid populations to long-term selection has not often been explored in the lab. To fill this knowledge gap we crossed the two most distantly related members of the Saccharomyces sensu stricto group, S. cerevisiae and S. uvarum, and established a mixed population of homoploid and aneuploid hybrids to study how different types of selection impact hybrid genome structure.
UR - http://www.scopus.com/inward/record.url?scp=84859133877&partnerID=8YFLogxK
U2 - 10.1186/1471-2148-12-46
DO - 10.1186/1471-2148-12-46
M3 - Article
C2 - 22471618
AN - SCOPUS:84859133877
SN - 1471-2148
VL - 12
JO - BMC Evolutionary Biology
JF - BMC Evolutionary Biology
IS - 1
M1 - 46
ER -