Double activation preparation of an acridinyl-isoxazolyl-lexitropsin

Peiwen Zhou, Michael D. Mosher, Wendy D. Taylor, Gregory A. Crawford, N. R. Natale

Research output: Contribution to journalArticlepeer-review

Abstract

The coupling of a sterically hindered acridinyl isoxazole ester directly to the amine group of a lexitropsin is significantly improved by double activation, using trimethylaluminum to activate the amine portion and samarium (III) chloride to enhance the carboxylate reactivity.

Original languageEnglish
Pages (from-to)2455-2456
Number of pages2
JournalBioorganic and Medicinal Chemistry Letters
Volume7
Issue number19
DOIs
StatePublished - Oct 7 1997

Fingerprint

Dive into the research topics of 'Double activation preparation of an acridinyl-isoxazolyl-lexitropsin'. Together they form a unique fingerprint.

Cite this