TY - JOUR
T1 - Electrical myostimulation (EMS) improves glucose metabolism and oxygen uptake in type 2 diabetes mellitus patients - Results from the EMS study
AU - Van Buuren, Frank
AU - Horstkotte, Dieter
AU - Mellwig, Klaus Peter
AU - Fründ, Andreas
AU - Vlachojannis, Marios
AU - Bogunovic, Nicola
AU - Dimitriadis, Zisis
AU - Vortherms, Jürgen
AU - Humphrey, Reed
AU - Niebauer, Josef
N1 - Publisher Copyright:
© 2015, Mary Ann Liebert, Inc.
PY - 2015/6/1
Y1 - 2015/6/1
N2 - Aims: In patients with type 2 diabetes mellitus (T2DM) exercise training is recommended to improve glycemic control. Electrical myostimulation (EMS) of skeletal muscles is a new method to increase exercise capacity in patients with chronic heart failure. The aim of this study was to investigate the effects of EMS in T2DM on glucose metabolism, body composition, and exercise performance using a newly designed stimulation suit that involves trunk, leg, and arm muscles. Subjects and Methods: Fifteen individuals (nine males; 61.7±14.8 years old) were trained for 10 weeks twice weekly for 20? min with EMS. Effects on glucose, glycosylated hemoglobin (HbA1c), oxygen consumption, and body composition were evaluated. Results: There was a significant increase of oxygen uptake at the aerobic threshold from 12.3±0.8 to 13.3±0.7? mL/kg/min (P=0.003) and of maximal work capacity from 96.9±6.4 to 101.4±7.9? W (P=0.046), with a concomitant trend for improved maximal oxygen uptake (from 14.5±0.9 to 14.7±0.9? mL/kg/min [P=0.059]). Fasting blood glucose level decreased from 164.0±12.5 to 133.4±9.9? mg/dL (P=0.001), and HbA1c level decreased from 7.7±0.3% to 7.2±0.3% (P=0.041), whereas mean total weight (from 101.5±4.0 to 103.1±4.3? kg) and proportion of body fat (from 38.8±3.2% to 40.3±3.4%) remained statistically unchanged. Conclusions: EMS can improve glucose metabolism and functional performance in T2DM patients. These data suggest that EMS might emerge as a novel additional therapeutic mode of exercise training and might help patients to overcome their sedentary lifestyle.
AB - Aims: In patients with type 2 diabetes mellitus (T2DM) exercise training is recommended to improve glycemic control. Electrical myostimulation (EMS) of skeletal muscles is a new method to increase exercise capacity in patients with chronic heart failure. The aim of this study was to investigate the effects of EMS in T2DM on glucose metabolism, body composition, and exercise performance using a newly designed stimulation suit that involves trunk, leg, and arm muscles. Subjects and Methods: Fifteen individuals (nine males; 61.7±14.8 years old) were trained for 10 weeks twice weekly for 20? min with EMS. Effects on glucose, glycosylated hemoglobin (HbA1c), oxygen consumption, and body composition were evaluated. Results: There was a significant increase of oxygen uptake at the aerobic threshold from 12.3±0.8 to 13.3±0.7? mL/kg/min (P=0.003) and of maximal work capacity from 96.9±6.4 to 101.4±7.9? W (P=0.046), with a concomitant trend for improved maximal oxygen uptake (from 14.5±0.9 to 14.7±0.9? mL/kg/min [P=0.059]). Fasting blood glucose level decreased from 164.0±12.5 to 133.4±9.9? mg/dL (P=0.001), and HbA1c level decreased from 7.7±0.3% to 7.2±0.3% (P=0.041), whereas mean total weight (from 101.5±4.0 to 103.1±4.3? kg) and proportion of body fat (from 38.8±3.2% to 40.3±3.4%) remained statistically unchanged. Conclusions: EMS can improve glucose metabolism and functional performance in T2DM patients. These data suggest that EMS might emerge as a novel additional therapeutic mode of exercise training and might help patients to overcome their sedentary lifestyle.
UR - http://www.scopus.com/inward/record.url?scp=84929257917&partnerID=8YFLogxK
U2 - 10.1089/dia.2014.0315
DO - 10.1089/dia.2014.0315
M3 - Article
C2 - 25734937
AN - SCOPUS:84929257917
SN - 1520-9156
VL - 17
SP - 413
EP - 419
JO - Diabetes Technology and Therapeutics
JF - Diabetes Technology and Therapeutics
IS - 6
ER -
