Evaluation and Management Outcomes and Burdens in Patients with Refractory Chronic Cough Referred for Behavioral Cough Suppression Therapy

Laurie J. Slovarp; Marie E. Jetté; Amanda I. Gillespie; Jane E. Reynolds; Julie M. Barkmeier-Kraemer

doi:10.1007/s00408-021-00442-w

Evaluation and Management Outcomes and Burdens in Patients with Refractory Chronic Cough Referred for Behavioral Cough Suppression Therapy

Laurie J. Slovarp
, Marie E. Jetté
, Amanda I. Gillespie
, Jane E. Reynolds
, Julie M. Barkmeier-Kraemer

School of Speech, Language, Hearing and Occupational Sciences

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Purpose: The purpose of this study was to investigate the typical symptoms and medical management characteristics of adult patients with refractory chronic cough (RCC) who are referred to speech-language pathology (SLP) for behavioral cough suppression therapy (BCST) in order to estimate cost-effectiveness and efficiency of current practice patterns for this population. Methods: One hundred sixty-four (164) patients with RCC referred for BCST were surveyed. Patients completed an initial survey at BCST onset related to symptom pattern and prior treatment, including the Leicester Cough Questionnaire (LCQ). Every four to six weeks patients completed follow-up surveys to assess their response to BCST. Results: Mean age was 58 years (83.5% women). The majority of patients reported their cough began two or more years prior to BCST. Approximately half (49%) reported seeing four or more physicians (including primary care physicians) and being prescribed four or more medications (57%) prior to BCST. Medications targeting post-nasal drip (72%), reflux (70%), asthma (56%), and allergies (56%) were most commonly prescribed. BCST resulted in a clinically significant improvement in 70.1% of participants. The mean change in LCQ for those who improved with BCST was 6.61. Over half (58%) reported they were quite satisfied to completely satisfied with their treatment response. The average time from enrollment to study completion was 64 days. Conclusion: The results of this study suggest early intervention with BCST may be a cost-effective and efficient option for patients with RCC.

Original language	English
Pages (from-to)	263-271
Number of pages	9
Journal	Lung
Volume	199
Issue number	3
DOIs	https://doi.org/10.1007/s00408-021-00442-w
State	Published - Jun 2021

Funding

The authors would like to thank the following for their assistance with recruitment for this study: Lynn Harris, MS, CCC-SLP, Carol Cady, MD, Jennifer Andrus, MD, Peter Belafsky, MD, Krishna Sundar, MD, Eric Stern, MD, Megan Walker, MS, CCC-SLP, Lisa D’Oyley, MS, CCC-SLP, Jennifer Spielman, MA, CCC-SLP, Anne Vertigan, PhD, Joy Hesse, MA, CCC-SLP, Mary Spremulli, MA, CCC-SLP, Kristie Miner, SLP, Karen Cox, SLP, Michele Payton Marsh, SLP. The authors also acknowledge the following students who were instrumental in collecting and collating the data: Emma Bozarth, Sarah Popp. This research was funded by the Mountain West Clinical Translational Infrastructure Network and the Montana IDeA Network of Biomedical Research Excellence through grants from the National Institute of General Medical Sciences of the National Institutes of Health: #: 1U54GM104944 and P20GM103474, respectfully. The content in this publication is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Funder number
1U54GM104944
P20GM103474

Keywords

Behavioral cough suppression therapy (BCST)
Chronic cough
Cost-effectiveness
Refractory chronic cough (RCC)
Speech-language-pathology (SLP)

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10.1007/s00408-021-00442-w

Cite this

@article{1ccda7f89a794187b9ee79fe5cf7b0bb,

title = "Evaluation and Management Outcomes and Burdens in Patients with Refractory Chronic Cough Referred for Behavioral Cough Suppression Therapy",

abstract = "Purpose: The purpose of this study was to investigate the typical symptoms and medical management characteristics of adult patients with refractory chronic cough (RCC) who are referred to speech-language pathology (SLP) for behavioral cough suppression therapy (BCST) in order to estimate cost-effectiveness and efficiency of current practice patterns for this population. Methods: One hundred sixty-four (164) patients with RCC referred for BCST were surveyed. Patients completed an initial survey at BCST onset related to symptom pattern and prior treatment, including the Leicester Cough Questionnaire (LCQ). Every four to six weeks patients completed follow-up surveys to assess their response to BCST. Results: Mean age was 58 years (83.5\% women). The majority of patients reported their cough began two or more years prior to BCST. Approximately half (49\%) reported seeing four or more physicians (including primary care physicians) and being prescribed four or more medications (57\%) prior to BCST. Medications targeting post-nasal drip (72\%), reflux (70\%), asthma (56\%), and allergies (56\%) were most commonly prescribed. BCST resulted in a clinically significant improvement in 70.1\% of participants. The mean change in LCQ for those who improved with BCST was 6.61. Over half (58\%) reported they were quite satisfied to completely satisfied with their treatment response. The average time from enrollment to study completion was 64 days. Conclusion: The results of this study suggest early intervention with BCST may be a cost-effective and efficient option for patients with RCC.",

keywords = "Behavioral cough suppression therapy (BCST), Chronic cough, Cost-effectiveness, Refractory chronic cough (RCC), Speech-language-pathology (SLP)",

author = "Slovarp, \{Laurie J.\} and Jett{\'e}, \{Marie E.\} and Gillespie, \{Amanda I.\} and Reynolds, \{Jane E.\} and Barkmeier-Kraemer, \{Julie M.\}",

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year = "2021",

month = jun,

doi = "10.1007/s00408-021-00442-w",

language = "English",

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pages = "263--271",

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T1 - Evaluation and Management Outcomes and Burdens in Patients with Refractory Chronic Cough Referred for Behavioral Cough Suppression Therapy

AU - Slovarp, Laurie J.

AU - Jetté, Marie E.

AU - Gillespie, Amanda I.

AU - Reynolds, Jane E.

AU - Barkmeier-Kraemer, Julie M.

PY - 2021/6

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N2 - Purpose: The purpose of this study was to investigate the typical symptoms and medical management characteristics of adult patients with refractory chronic cough (RCC) who are referred to speech-language pathology (SLP) for behavioral cough suppression therapy (BCST) in order to estimate cost-effectiveness and efficiency of current practice patterns for this population. Methods: One hundred sixty-four (164) patients with RCC referred for BCST were surveyed. Patients completed an initial survey at BCST onset related to symptom pattern and prior treatment, including the Leicester Cough Questionnaire (LCQ). Every four to six weeks patients completed follow-up surveys to assess their response to BCST. Results: Mean age was 58 years (83.5% women). The majority of patients reported their cough began two or more years prior to BCST. Approximately half (49%) reported seeing four or more physicians (including primary care physicians) and being prescribed four or more medications (57%) prior to BCST. Medications targeting post-nasal drip (72%), reflux (70%), asthma (56%), and allergies (56%) were most commonly prescribed. BCST resulted in a clinically significant improvement in 70.1% of participants. The mean change in LCQ for those who improved with BCST was 6.61. Over half (58%) reported they were quite satisfied to completely satisfied with their treatment response. The average time from enrollment to study completion was 64 days. Conclusion: The results of this study suggest early intervention with BCST may be a cost-effective and efficient option for patients with RCC.

AB - Purpose: The purpose of this study was to investigate the typical symptoms and medical management characteristics of adult patients with refractory chronic cough (RCC) who are referred to speech-language pathology (SLP) for behavioral cough suppression therapy (BCST) in order to estimate cost-effectiveness and efficiency of current practice patterns for this population. Methods: One hundred sixty-four (164) patients with RCC referred for BCST were surveyed. Patients completed an initial survey at BCST onset related to symptom pattern and prior treatment, including the Leicester Cough Questionnaire (LCQ). Every four to six weeks patients completed follow-up surveys to assess their response to BCST. Results: Mean age was 58 years (83.5% women). The majority of patients reported their cough began two or more years prior to BCST. Approximately half (49%) reported seeing four or more physicians (including primary care physicians) and being prescribed four or more medications (57%) prior to BCST. Medications targeting post-nasal drip (72%), reflux (70%), asthma (56%), and allergies (56%) were most commonly prescribed. BCST resulted in a clinically significant improvement in 70.1% of participants. The mean change in LCQ for those who improved with BCST was 6.61. Over half (58%) reported they were quite satisfied to completely satisfied with their treatment response. The average time from enrollment to study completion was 64 days. Conclusion: The results of this study suggest early intervention with BCST may be a cost-effective and efficient option for patients with RCC.

KW - Behavioral cough suppression therapy (BCST)

KW - Chronic cough

KW - Cost-effectiveness

KW - Refractory chronic cough (RCC)

KW - Speech-language-pathology (SLP)

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ER -

Evaluation and Management Outcomes and Burdens in Patients with Refractory Chronic Cough Referred for Behavioral Cough Suppression Therapy

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