Fighting Flies: Quantifying and Analyzing Drosophila Aggression

Maria P. Fernandez, Severine Trannoy, Sarah J. Certel

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Aggression is an innate behavior that likely evolved in the framework of defending or obtaining resources. This complex social behavior is influenced by genetic, environmental, and internal factors. Drosophila melanogaster remains an effective and exciting model organism with which to unravel the mechanistic basis of aggression due to its small but sophisticated brain, an impressive array of neurogenetic tools, and robust stereotypical behavioral patterns. The investigations of many laboratories have led to the identification of external and internal state factors that promote aggression, sex differences in the patterns and outcome of aggression, and neurotransmitters that regulate aggression.

Original languageEnglish
Pages (from-to)618-627
Number of pages10
JournalCold Spring Harbor Protocols
Issue number9
StatePublished - Sep 1 2023


  • Animals
  • Female
  • Male
  • Drosophila
  • Drosophila melanogaster/genetics
  • Social Behavior
  • Aggression
  • Behavior, Animal/physiology
  • Drosophila Proteins


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