A new framework (GenApp) for rapid generation of scientific applications running on a variety of systems including science gateways has recently been developed. This framework builds a user interface for a variety of target environments on a collection of executable modules. The method for execution of the modules is unrestricted by the framework. Initial implementation supports direct execution, and not queue managed submission, on a user's workstation, a web server, or a compute resource accessible from the web server. After a successful workshop, it was discovered that long running jobs would sometimes fail, due to the loss of a TCP connection. This precipitated an improvement to the execution method with the bonus of easily allowing multiple web clients to attach to the running job. Finally, to support a diversity of queue managed compute resources, a Google Summer of Code project was completed to integrate the Apache Airavata middleware as an additional execution model within the GenApp framework.