TY - JOUR
T1 - Immune changes
T2 - 2 h of continuous vs. intermittent cycling
AU - Nieman, David
AU - Henson, D.
AU - Gojanovich, G.
AU - Davis, J. M.
AU - Dumke, C.
AU - Utter, A.
AU - Murphy, A.
AU - Pearce, S.
AU - McAnulty, S.
AU - McAnulty, L.
PY - 2007/7
Y1 - 2007/7
N2 - Immune changes following 2 h of intensive cycling with or without rest intervals were measured in trained cyclists (n = 12) who functioned as their own controls during two test sessions that were separated by two weeks. Subjects cycled for 2.0 h at ∼64% Wattsmax continuously (C) or with 3-min rest intervals (R) interspersed every 10 min (2.6 h total time), with the order of the sessions randomized. Blood samples were collected 30-min pre-exercise, and immediately and 1-h postexercise, and assayed for blood leukocyte subset counts, plasma IL-6, IL-10, IL-1ra, IL-8, PHA-induced lymphocyte proliferation, and natural killer cell activity (NKCA). Significant time effects were measured for all immune measures, but no significant differences in the pattern of change were found between C and R exercise trials. In conclusion, immune changes induced by 2 h of intense and prolonged exercise paralleled those measured when athletes rested 3 min every 10 min of exercise.
AB - Immune changes following 2 h of intensive cycling with or without rest intervals were measured in trained cyclists (n = 12) who functioned as their own controls during two test sessions that were separated by two weeks. Subjects cycled for 2.0 h at ∼64% Wattsmax continuously (C) or with 3-min rest intervals (R) interspersed every 10 min (2.6 h total time), with the order of the sessions randomized. Blood samples were collected 30-min pre-exercise, and immediately and 1-h postexercise, and assayed for blood leukocyte subset counts, plasma IL-6, IL-10, IL-1ra, IL-8, PHA-induced lymphocyte proliferation, and natural killer cell activity (NKCA). Significant time effects were measured for all immune measures, but no significant differences in the pattern of change were found between C and R exercise trials. In conclusion, immune changes induced by 2 h of intense and prolonged exercise paralleled those measured when athletes rested 3 min every 10 min of exercise.
KW - Cytokines
KW - Exercise
KW - Lymphocytes
KW - Natural killer cell activity
UR - http://www.scopus.com/inward/record.url?scp=34447536817&partnerID=8YFLogxK
U2 - 10.1055/s-2007-964856
DO - 10.1055/s-2007-964856
M3 - Article
C2 - 17373603
AN - SCOPUS:34447536817
SN - 0172-4622
VL - 28
SP - 625
EP - 630
JO - International Journal of Sports Medicine
JF - International Journal of Sports Medicine
IS - 7
ER -