Isolation, Structure Elucidation, and Partial Synthesis of Xestosterol, a Biosynthetically Significant Sterol from the Sponge Xestospongia muta

W. C.M.C. Kokke; Claudio Tarchini; Donald B. Stierle; Carl Djerassi

doi:10.1021/jo01333a023

Isolation, Structure Elucidation, and Partial Synthesis of Xestosterol, a Biosynthetically Significant Sterol from the Sponge Xestospongia muta

W. C.M.C. Kokke
, Claudio Tarchini
, Donald B. Stierle
, Carl Djerassi

University of California at San Diego

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Abstract

The major component of the sterol constituents of the Carribean sponge Xestospongia muta is a new C30 sterol-xestosterol-characterized by the “elongated” side chain depicted by structure 6, as was confirmed by partial synthesis. The probable biological function of 6 or similar sterols in sponges is emphasized.

Original language	English
Pages (from-to)	3385-3388
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	44
Issue number	19
DOIs	https://doi.org/10.1021/jo01333a023
State	Published - 1979

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title = "Isolation, Structure Elucidation, and Partial Synthesis of Xestosterol, a Biosynthetically Significant Sterol from the Sponge Xestospongia muta",

abstract = "The major component of the sterol constituents of the Carribean sponge Xestospongia muta is a new C30 sterol-xestosterol-characterized by the “elongated” side chain depicted by structure 6, as was confirmed by partial synthesis. The probable biological function of 6 or similar sterols in sponges is emphasized.",

author = "Kokke, \{W. C.M.C.\} and Claudio Tarchini and Stierle, \{Donald B.\} and Carl Djerassi",

year = "1979",

doi = "10.1021/jo01333a023",

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volume = "44",

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journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

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AU - Kokke, W. C.M.C.

AU - Tarchini, Claudio

AU - Stierle, Donald B.

AU - Djerassi, Carl

PY - 1979

Y1 - 1979

N2 - The major component of the sterol constituents of the Carribean sponge Xestospongia muta is a new C30 sterol-xestosterol-characterized by the “elongated” side chain depicted by structure 6, as was confirmed by partial synthesis. The probable biological function of 6 or similar sterols in sponges is emphasized.

AB - The major component of the sterol constituents of the Carribean sponge Xestospongia muta is a new C30 sterol-xestosterol-characterized by the “elongated” side chain depicted by structure 6, as was confirmed by partial synthesis. The probable biological function of 6 or similar sterols in sponges is emphasized.

UR - https://www.scopus.com/pages/publications/0018572629

U2 - 10.1021/jo01333a023

DO - 10.1021/jo01333a023

M3 - Article

AN - SCOPUS:0018572629

SN - 0022-3263

VL - 44

SP - 3385

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JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 19

ER -

Isolation, Structure Elucidation, and Partial Synthesis of Xestosterol, a Biosynthetically Significant Sterol from the Sponge Xestospongia muta

Abstract

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