Kimbasines A and B, novel hexacyclic norsesterterpene alkaloids from the sponge Igernella notabilis

John H. Cardellina, Robert L. Hendrickson, Andrea A. Stierle, Gary E. Martin

Research output: Contribution to journalArticlepeer-review

Abstract

Two novel hexacyclic norsesterterpene alkaloids, kimbasines A and B, have been isolated from cytotoxic extracts of the sponge Igernella notabilis. The structures, related as butyrate and acetate esters, were solved by analyses of spectral data of kimbasine A and comparison of data for kimbasine B with those of kimbasine A. Biological testing data for kimbasine A are presented.

Original languageEnglish
Pages (from-to)2347-2350
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number21
DOIs
StatePublished - May 20 1991

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