Mechanisms of exercise-induced cardioprotection

Scott K. Powers, Ashley J. Smuder, Andreas N. Kavazis, John C. Quindry

Research output: Contribution to journalReview articlepeer-review

112 Scopus citations

Abstract

Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major pathological event leading to morbidity and mortality in those with coronary artery disease. Interestingly, as few as five bouts of exercise on consecutive days can rapidly produce a cardiac phenotype that resists IR-induced myocardial injury. This review summarizes the development of exercise-induced cardioprotection and the mechanisms responsible for this important adaptive response.

Original languageEnglish
Pages (from-to)27-38
Number of pages12
JournalPhysiology
Volume29
Issue number1
DOIs
StatePublished - Jan 1 2014

Fingerprint

Dive into the research topics of 'Mechanisms of exercise-induced cardioprotection'. Together they form a unique fingerprint.

Cite this