Mechanisms of exercise-induced cardioprotection

Scott K. Powers, Ashley J. Smuder, Andreas N. Kavazis, John C. Quindry

Research output: Contribution to journalReview articlepeer-review

112 Scopus citations


Myocardial ischemia-reperfusion (IR) injury can cause ventricular cell death and is a major pathological event leading to morbidity and mortality in those with coronary artery disease. Interestingly, as few as five bouts of exercise on consecutive days can rapidly produce a cardiac phenotype that resists IR-induced myocardial injury. This review summarizes the development of exercise-induced cardioprotection and the mechanisms responsible for this important adaptive response.

Original languageEnglish
Pages (from-to)27-38
Number of pages12
Issue number1
StatePublished - Jan 1 2014


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