TY - JOUR
T1 - Medication-Nutrient Interactions
T2 - Hypophosphatemia Associated With Sucralfate in the Intensive Care Unit
AU - Miller, Sarah Johnston
AU - Simpson, Jeff
PY - 1991/10
Y1 - 1991/10
N2 - Clinically significant medication-nutrient interactions are of concern to the nutritional support practitioner. To emphasize the possible effect of the aluminum-containing medication sucralfate on serum phosphorus levels, patients admitted to the intensive care unit of a small private hospital were monitored for a 4-week period. Sixteen patients demonstrated low serum phosphorus levels; eight (50%) of these were receiving sucralfate. Eighteen patients had no low phosphorus levels measured; five (28%) patients in this group were receiving sucralfate. The hypophosphatemia observed in these patients was probably multifactorial; respiratory alkalosis and dextrose feeding as well as sucralfate use are consistent with hypophosphatemia.
AB - Clinically significant medication-nutrient interactions are of concern to the nutritional support practitioner. To emphasize the possible effect of the aluminum-containing medication sucralfate on serum phosphorus levels, patients admitted to the intensive care unit of a small private hospital were monitored for a 4-week period. Sixteen patients demonstrated low serum phosphorus levels; eight (50%) of these were receiving sucralfate. Eighteen patients had no low phosphorus levels measured; five (28%) patients in this group were receiving sucralfate. The hypophosphatemia observed in these patients was probably multifactorial; respiratory alkalosis and dextrose feeding as well as sucralfate use are consistent with hypophosphatemia.
UR - http://www.scopus.com/inward/record.url?scp=0026234229&partnerID=8YFLogxK
U2 - 10.1177/0115426591006005199
DO - 10.1177/0115426591006005199
M3 - Article
C2 - 1775116
AN - SCOPUS:0026234229
SN - 0884-5336
VL - 6
SP - 199
EP - 201
JO - Nutrition in Clinical Practice
JF - Nutrition in Clinical Practice
IS - 5
ER -