Metabolites of the Marine Sponge Laxosuberites sp.

Donald B. Stierle, D. John Faulkner

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


The marine sponge Laxosuberites sp. contained a mixture of four 5-alkylpyrrole-2-carboxaldehydes 1, (6'Z)-5-(12'-cyano-6'-dodecenyl)pyrrole-2-carboxaldehyde (2), and (6'Z)-5-(23'-cyano-23'-hydroxy-6'-tricosenyl) pyrrole-2-carboxaldehyde (3). The structures of the metabolites were determined by interpretation of spectral data and by chemical degradation. The cyanohydrin 3 is unusually stable to normal isolation and storage procedures.

Original languageEnglish
Pages (from-to)4980-4982
Number of pages3
JournalJournal of Organic Chemistry
Issue number24
StatePublished - Nov 1980


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