Micelle Polymers as Pseudostationary Phases in MEKC: Chromatographic Performance and Chemical Selectivity

Christopher P. Palmer, Shigeru Terabe

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Two micelle polymers, sodium polyundecenyl sulfate and sodium polyundecylenate, have been synthesized, purified, and characterized as pseudostationary phases for micellar electrokinetic chromatography. The polymers have been characterized by size exclusion chromatography, laser light scattering, and electrokinetic chromatography. When employed as pseudostationary phases, the micelle polymers were found to provide selective and efficient separations. In aqueous buffers, the chromato graphic properties of the polymers were similar to those of sodium dodecyl sulfate (SDS) micelles. The efficiency was found to be similar to that of SDS micelles. The electrophoretic mobility of the polymers was greater than SDS micelles, providing an extended migration time range. The chemical selectivity of the two polymers was found to be very similar. However, both of the polymers are more polar than SDS micelles. In buffers modified with high concentrations of organic solvents, the chromatographic properties of sodium polyundecenyl sulfate were found to be superior to those of SDS micelles. Separations of polynuclear aromatic hydrocarbons in acetonitrile- and methanol-modified buffers are much improved using the sulfate polymer relative to SDS micelles. The structural selectivity of the undecenyl sulfate polymer pseudostationary phase for the separation of polynuclear aromatic hydrocarbons in organic-modified buffer media was found to be affected by the organic modifier used.

Original languageEnglish
Pages (from-to)1852-1860
Number of pages9
JournalAnalytical Chemistry
Issue number10
StatePublished - May 15 1997


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