TY - JOUR
T1 - Microscale liquid phase separations
AU - Palmer, Christopher P.
AU - Remcho, Vincent T.
PY - 2002
Y1 - 2002
N2 - Miniaturization and microfabrication of analytical instrumentation for chemical and biological analysis has gained momentum with the introduction and application of microfabricated instruments. Developments in CEC, capillary LC, CE, and MEKC provide a range of selectivities and separation mechanisms that extend the reach of microscale separations to encompass a large pool of prospective analytes and matrices. Detection technologies include off-chip UV or mass spectrometric (MS) detection and on-chip fluorescence and electrochemical detection. Surface modifications can also be made to facilitate sorption of analytes on the channel walls, such that open tubular capillary electrochromatography (CEC) separations can be achieved.
AB - Miniaturization and microfabrication of analytical instrumentation for chemical and biological analysis has gained momentum with the introduction and application of microfabricated instruments. Developments in CEC, capillary LC, CE, and MEKC provide a range of selectivities and separation mechanisms that extend the reach of microscale separations to encompass a large pool of prospective analytes and matrices. Detection technologies include off-chip UV or mass spectrometric (MS) detection and on-chip fluorescence and electrochemical detection. Surface modifications can also be made to facilitate sorption of analytes on the channel walls, such that open tubular capillary electrochromatography (CEC) separations can be achieved.
UR - http://www.scopus.com/inward/record.url?scp=0012897305&partnerID=8YFLogxK
U2 - 10.1007/s00216-001-1154-1
DO - 10.1007/s00216-001-1154-1
M3 - Article
C2 - 11939207
AN - SCOPUS:0012897305
SN - 1618-2642
VL - 372
SP - 35
EP - 36
JO - Analytical and Bioanalytical Chemistry
JF - Analytical and Bioanalytical Chemistry
IS - 1
ER -