We present a simple model of experimental setup for in vitro study of drug release from drug eluting stents and drug propagation in artificial tissue samples representing blood vessels. The model is further reduced using the assumption on vastly different characteristic diffusion times in the stent coating and in the artificial tissue. The model is used to derive a relationship between the times at which the measurements have to be taken for two experimental platforms, with corresponding artificial tissue samples made of different materials with different drug diffusion coefficients, to properly compare the drug release characteristics of drug eluting stents.
|Journal of Physics: Conference Series
|Published - Jul 1 2016
|7th International Workshop on MUlti-Rate Processes and HYSteresis, MURPHYS 2014 in conjunction with the 2nd International Workshop on Hysteresis and Slow-Fast Systems, HSFS 2014 - Berlin, Germany
Duration: Apr 7 2014 → Apr 11 2014