Nanoparticulate poly(Glucaramide)-based hydrogels for controlled release applications

Erik R. Johnston; Tyler N. Smith; Monica A. Serban

doi:10.3390/gels3020017

Nanoparticulate poly(Glucaramide)-based hydrogels for controlled release applications

Erik R. Johnston
, Tyler N. Smith
, Monica A. Serban

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

In 2004, D-Glucaric acid (GA) was identified as one of the top value-added chemicals from renewable feedstocks. For this study, a patented synthetic method was used to obtain gel forming polymers through the polycondensation of GA and several aliphatic diamines. The first time characterization and a potential practical application of such hydrogels is reported herein. Our findings indicate that the physical properties and gelling abilities of these materials correlate with the chemical structure of the precursor diamines used for polymerization. The hydrogels appear to have nanoparticulate nature, form via aggregation, are thermoresponsive, and appear suitable as controlled release systems for small molecules. Overall, this study further highlights the versatility of GA as a building block for the synthesis of sustainable materials, with potential for a wide array of applications.

Original language	English
Article number	17
Journal	Gels
Volume	3
Issue number	2
DOIs	https://doi.org/10.3390/gels3020017
State	Published - Jun 2017

Funding

Acknowledgments: Images, electron microscopy services and resources were provided by the Electron Microscopy Facility, Division of Biological Sciences, University of Montana, Missoula, MT. The EM Facility is supported, in part, by grant #RR-16455-04 from the National Center for Research Resources (Biomedical Research Infrastructure Network program), National Institutes of Health. Funding Sources: The research presented here was supported in part by Rivertop Renewables, Missoula, MT, USA.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 7 Affordable and Clean Energy

Keywords

Controlled release
D-Glucaric acid
Hydrogel
Nanoparticles
Polymers

Access to Document

10.3390/gels3020017

Cite this

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title = "Nanoparticulate poly(Glucaramide)-based hydrogels for controlled release applications",

abstract = "In 2004, D-Glucaric acid (GA) was identified as one of the top value-added chemicals from renewable feedstocks. For this study, a patented synthetic method was used to obtain gel forming polymers through the polycondensation of GA and several aliphatic diamines. The first time characterization and a potential practical application of such hydrogels is reported herein. Our findings indicate that the physical properties and gelling abilities of these materials correlate with the chemical structure of the precursor diamines used for polymerization. The hydrogels appear to have nanoparticulate nature, form via aggregation, are thermoresponsive, and appear suitable as controlled release systems for small molecules. Overall, this study further highlights the versatility of GA as a building block for the synthesis of sustainable materials, with potential for a wide array of applications.",

keywords = "Controlled release, D-Glucaric acid, Hydrogel, Nanoparticles, Polymers",

author = "Johnston, \{Erik R.\} and Smith, \{Tyler N.\} and Serban, \{Monica A.\}",

note = "Publisher Copyright: {\textcopyright} 2017 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2017",

month = jun,

doi = "10.3390/gels3020017",

language = "English",

volume = "3",

journal = "Gels",

issn = "2310-2861",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "2",

}

TY - JOUR

T1 - Nanoparticulate poly(Glucaramide)-based hydrogels for controlled release applications

AU - Johnston, Erik R.

AU - Smith, Tyler N.

AU - Serban, Monica A.

PY - 2017/6

Y1 - 2017/6

N2 - In 2004, D-Glucaric acid (GA) was identified as one of the top value-added chemicals from renewable feedstocks. For this study, a patented synthetic method was used to obtain gel forming polymers through the polycondensation of GA and several aliphatic diamines. The first time characterization and a potential practical application of such hydrogels is reported herein. Our findings indicate that the physical properties and gelling abilities of these materials correlate with the chemical structure of the precursor diamines used for polymerization. The hydrogels appear to have nanoparticulate nature, form via aggregation, are thermoresponsive, and appear suitable as controlled release systems for small molecules. Overall, this study further highlights the versatility of GA as a building block for the synthesis of sustainable materials, with potential for a wide array of applications.

AB - In 2004, D-Glucaric acid (GA) was identified as one of the top value-added chemicals from renewable feedstocks. For this study, a patented synthetic method was used to obtain gel forming polymers through the polycondensation of GA and several aliphatic diamines. The first time characterization and a potential practical application of such hydrogels is reported herein. Our findings indicate that the physical properties and gelling abilities of these materials correlate with the chemical structure of the precursor diamines used for polymerization. The hydrogels appear to have nanoparticulate nature, form via aggregation, are thermoresponsive, and appear suitable as controlled release systems for small molecules. Overall, this study further highlights the versatility of GA as a building block for the synthesis of sustainable materials, with potential for a wide array of applications.

KW - Controlled release

KW - D-Glucaric acid

KW - Hydrogel

KW - Nanoparticles

KW - Polymers

UR - https://www.scopus.com/pages/publications/85111399897

U2 - 10.3390/gels3020017

DO - 10.3390/gels3020017

M3 - Article

AN - SCOPUS:85111399897

SN - 2310-2861

VL - 3

JO - Gels

JF - Gels

IS - 2

M1 - 17

ER -

Nanoparticulate poly(Glucaramide)-based hydrogels for controlled release applications

Abstract

Funding

UN SDGs

Keywords

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