New synthetic retinoids obtained by palladium-catalyzed tandem cyclisation-hydride capture process

Philippe Diaz, Fabrice Gendre, Lucien Stella, Bruno Charpentier

Research output: Contribution to journalArticlepeer-review

Abstract

A new series of conformationally restricted retinoids (3-aryl-3-methyl- 2,3-dihydrobenzofurans) have been prepared through a palladium-catalyzed tandem cyclisation-hydride capture. The use of enantiopure BINAP-Pd catalyst allowed asymmetric synthesis of bioactive molecules.

Original languageEnglish
Pages (from-to)4579-4590
Number of pages12
JournalTetrahedron
Volume54
Issue number18
DOIs
StatePublished - Apr 30 1998

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