Abstract
A new series of conformationally restricted retinoids (3-aryl-3-methyl- 2,3-dihydrobenzofurans) have been prepared through a palladium-catalyzed tandem cyclisation-hydride capture. The use of enantiopure BINAP-Pd catalyst allowed asymmetric synthesis of bioactive molecules.
Original language | English |
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Pages (from-to) | 4579-4590 |
Number of pages | 12 |
Journal | Tetrahedron |
Volume | 54 |
Issue number | 18 |
DOIs | |
State | Published - Apr 30 1998 |