Novel alkyl-modified anionic siloxanes as pseudostationary phases for electrokinetic chromatography: III. Performance in organic-modified buffers

Dominic S. Peterson, Christopher P. Palmer

Research output: Contribution to journalArticlepeer-review

Abstract

Anionic water-soluble siloxanes modified with different amounts of alkyl chains have been used as pseudostationary phases in electrokinetic chromatography. Ionic siloxane polymers with attached alkyl chains of C8 and C12 and having different alkyl chain densities have been employed previously to achieve selective and efficient separations with a range of electrophoretic mobilities and methylene selectivities. In this study, the performance of three alkyl-modified siloxanes is examined in different organic-modified buffers and at differing amounts of organic modifier. The organic modifiers used are acetonitrile and methanol. The siloxanes are stable in these organic solvents and show good mobility and good methylene selectivities even at high concentration of organic solvent. Siloxanes have also been used to separate a mixture of 14 polynuclear aromatic hydrocarbons in an acetonitrile-modified buffer.

Original languageEnglish
Pages (from-to)255-261
Number of pages7
JournalJournal of Chromatography A
Volume959
Issue number1-2
DOIs
StatePublished - Jun 14 2002

Keywords

  • Alkyl phenyl ketones
  • Buffer composition
  • Electrokinetic chromatography
  • Polynuclear aromatic hydrocarbons
  • Pseudostationary phases
  • Siloxanes

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