Abstract
The preparation of the anion of a series of protected 3,5‐disubstituted 4‐isoxazolecarboxylic acids and the resulting addition of the anion to 9‐chloroacridine is described. The addition‐elimination reaction proceeds to give the expected acridinylmethylisoxazoles and has been justified based on calculated molecular mechanics energies and solvent effects.
| Original language | English |
|---|---|
| Pages (from-to) | 1385-1387 |
| Number of pages | 3 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 32 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1995 |
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