PICI thieves: Molecular piracy and cooperation

Amelia K. Schmidt; Dominick R. Faith; Patrick R. Secor

doi:10.1016/j.chom.2022.12.008

PICI thieves: Molecular piracy and cooperation

Amelia K. Schmidt
, Dominick R. Faith
, Patrick R. Secor

University of Montana

Research output: Contribution to journal › Comment/debate

2 Scopus citations

Abstract

Phage-inducible chromosomal islands (PICIs) steal structural proteins from helper phages. In two related studies, Penadés and coworkers reveal that PICIs are not parasites but mutualists. Some PICIs mobilize defense systems that restrict niche competitors, while other PICIs encode their own capsids and steal helper phage tails without affecting their fitness.

Original language	English
Pages (from-to)	3-5
Number of pages	3
Journal	Cell Host and Microbe
Volume	31
Issue number	1
DOIs	https://doi.org/10.1016/j.chom.2022.12.008
State	Published - Jan 11 2023

Funding

Author order was determined by heads or tails (of a coin, not a helper phage). We are grateful to the NIH (R01AI138981 and R01DK124317) for supporting our phage research. The authors declare no competing interests.

Funder number
R01DK124317, R01AI138981

Keywords

Genomic Islands
Bacteriophages/genetics
Capsid

Access to Document

10.1016/j.chom.2022.12.008

Cite this

@article{6c5c2a72869946c48dc9671bc5c52cb9,

title = "PICI thieves: Molecular piracy and cooperation",

abstract = "Phage-inducible chromosomal islands (PICIs) steal structural proteins from helper phages. In two related studies, Penad{\'e}s and coworkers reveal that PICIs are not parasites but mutualists. Some PICIs mobilize defense systems that restrict niche competitors, while other PICIs encode their own capsids and steal helper phage tails without affecting their fitness.",

keywords = "Genomic Islands, Bacteriophages/genetics, Capsid",

author = "Schmidt, \{Amelia K.\} and Faith, \{Dominick R.\} and Secor, \{Patrick R.\}",

year = "2023",

month = jan,

day = "11",

doi = "10.1016/j.chom.2022.12.008",

language = "English",

volume = "31",

pages = "3--5",

journal = "Cell Host and Microbe",

issn = "1931-3128",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - PICI thieves

T2 - Molecular piracy and cooperation

AU - Schmidt, Amelia K.

AU - Faith, Dominick R.

AU - Secor, Patrick R.

PY - 2023/1/11

Y1 - 2023/1/11

N2 - Phage-inducible chromosomal islands (PICIs) steal structural proteins from helper phages. In two related studies, Penadés and coworkers reveal that PICIs are not parasites but mutualists. Some PICIs mobilize defense systems that restrict niche competitors, while other PICIs encode their own capsids and steal helper phage tails without affecting their fitness.

AB - Phage-inducible chromosomal islands (PICIs) steal structural proteins from helper phages. In two related studies, Penadés and coworkers reveal that PICIs are not parasites but mutualists. Some PICIs mobilize defense systems that restrict niche competitors, while other PICIs encode their own capsids and steal helper phage tails without affecting their fitness.

KW - Genomic Islands

KW - Bacteriophages/genetics

KW - Capsid

UR - https://www.scopus.com/pages/publications/85144807783

U2 - 10.1016/j.chom.2022.12.008

DO - 10.1016/j.chom.2022.12.008

M3 - Comment/debate

C2 - 36634621

AN - SCOPUS:85144807783

SN - 1931-3128

VL - 31

SP - 3

EP - 5

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 1

ER -

PICI thieves: Molecular piracy and cooperation

Abstract

Funding

Keywords

Access to Document

Other files and links

Fingerprint

Cite this