Preparation of Keto-Isoxazole Polyketide Synthons

Jared K. Nelson; David J. Burkhart; Andrew McKenzie; Nicholas R. Natale

doi:10.1055/s-2003-42052

Preparation of Keto-Isoxazole Polyketide Synthons

Jared K. Nelson, David J. Burkhart, Andrew McKenzie, Nicholas R. Natale

University of Idaho

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

The Dess-Martin periodinane (DMP) oxidation of alcohols, proceeds in good to excellent yield in the presence of the isoxazole ring, and other nitrogen-containing functional groups. The DMP route allows for the preparation of highly branched polyketide synthetic equivalents.

Original language	English
Pages (from-to)	2213-2215
Number of pages	3
Journal	Synlett
Issue number	14
DOIs	https://doi.org/10.1055/s-2003-42052
State	Published - 2003

Keywords

Dihydropyridine
Isoxazole
Oxazoline
Oxidation
Periodinane

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10.1055/s-2003-42052

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title = "Preparation of Keto-Isoxazole Polyketide Synthons",

abstract = "The Dess-Martin periodinane (DMP) oxidation of alcohols, proceeds in good to excellent yield in the presence of the isoxazole ring, and other nitrogen-containing functional groups. The DMP route allows for the preparation of highly branched polyketide synthetic equivalents.",

keywords = "Dihydropyridine, Isoxazole, Oxazoline, Oxidation, Periodinane",

author = "Nelson, {Jared K.} and Burkhart, {David J.} and Andrew McKenzie and Natale, {Nicholas R.}",

year = "2003",

doi = "10.1055/s-2003-42052",

language = "English",

pages = "2213--2215",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

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T1 - Preparation of Keto-Isoxazole Polyketide Synthons

AU - Nelson, Jared K.

AU - Burkhart, David J.

AU - McKenzie, Andrew

AU - Natale, Nicholas R.

PY - 2003

Y1 - 2003

N2 - The Dess-Martin periodinane (DMP) oxidation of alcohols, proceeds in good to excellent yield in the presence of the isoxazole ring, and other nitrogen-containing functional groups. The DMP route allows for the preparation of highly branched polyketide synthetic equivalents.

AB - The Dess-Martin periodinane (DMP) oxidation of alcohols, proceeds in good to excellent yield in the presence of the isoxazole ring, and other nitrogen-containing functional groups. The DMP route allows for the preparation of highly branched polyketide synthetic equivalents.

KW - Dihydropyridine

KW - Isoxazole

KW - Oxazoline

KW - Oxidation

KW - Periodinane

UR - http://www.scopus.com/inward/record.url?scp=0344549623&partnerID=8YFLogxK

U2 - 10.1055/s-2003-42052

DO - 10.1055/s-2003-42052

M3 - Article

AN - SCOPUS:0344549623

SN - 0936-5214

SP - 2213

EP - 2215

JO - Synlett

JF - Synlett

IS - 14

ER -

Preparation of Keto-Isoxazole Polyketide Synthons

Abstract

Keywords

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