Preparation of Keto-Isoxazole Polyketide Synthons

Jared K. Nelson, David J. Burkhart, Andrew McKenzie, Nicholas R. Natale

Research output: Contribution to journalArticlepeer-review

Abstract

The Dess-Martin periodinane (DMP) oxidation of alcohols, proceeds in good to excellent yield in the presence of the isoxazole ring, and other nitrogen-containing functional groups. The DMP route allows for the preparation of highly branched polyketide synthetic equivalents.

Original languageEnglish
Pages (from-to)2213-2215
Number of pages3
JournalSynlett
Issue number14
DOIs
StatePublished - 2003

Keywords

  • Dihydropyridine
  • Isoxazole
  • Oxazoline
  • Oxidation
  • Periodinane

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