Abstract
The sponge Darwinella rosacea was found to harbor a host of marine microorganisms. One of these bacteria was identified as a marine Alteromonas species. The organic extract of this bacterium was antimicrobial, and the activity was traced to two novel pseudomonic acid derivatives 1 and 7. The structures of these compounds were elucidated by interpretation of the spectral data and extensive use of 2-dimensional NMR techniques and NOE studies on the parent compounds and the acetate derivatives 2 and 8.
Original language | English |
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Pages (from-to) | 1165-1169 |
Number of pages | 5 |
Journal | Experientia |
Volume | 48 |
Issue number | 11-12 |
DOIs | |
State | Published - Dec 1992 |
Keywords
- Alteromonas
- Darwinella rosacea
- Pseudomonic acid derivatives
- antimicrobial activity
- marine bacterium