@inbook{dda879ec5c9547cc8eeca09bb0c9fefe,
title = "Reduced Representation Methods for Subgenomic Enrichment and Next-Generation Sequencing",
abstract = "Several methods have been developed to enrich DNA for subsets of the genome prior to next-generation sequencing. These front-end enrichment strategies provide powerful and cost-effective tools for researchers interested in collecting large-scale genomic sequence data. In this review, I provide an overview of both general and targeted reduced representation enrichment strategies that are commonly used in tandem with next-generation sequencing. I focus on several key issues that are likely to be important when deciding which enrichment strategy is most appropriate for a given experiment. Overall, these techniques can enable the collection of large-scale genomic data in diverse species, providing a powerful tool for the study of evolutionary biology.",
keywords = "Ancient DNA, Reduced representation, Sample bar coding, Sequence capture, Targeted resequencing",
author = "Good, \{Jeffrey M.\}",
note = "Publisher Copyright: {\textcopyright} 2012, Springer Science+Business Media, LLC.",
year = "2011",
doi = "10.1007/978-1-61779-228-1\_5",
language = "English",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "85--103",
booktitle = "Methods in Molecular Biology",
}