Relationship between serum creatine kinase activity following exercise-induced muscle damage and muscle fibre composition

Meir Magal, Charles L. Dumke, Zea G. Urbiztondo, Michael J. Cavill, N. Travis Triplett, John C. Quindry, Jeff M. McBride, Yoram Epstein

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

In this study, we examined the relationship between serum creatine kinase activity following exercise-induced muscle damage and muscle fibre composition. Seventeen untrained males volunteered and underwent a VO2max test, Wingate test, and an exercise-induced muscle damage protocol.Muscle soreness and blood samples were recorded before, immediately after, and 24, 48, 72, and 96 h after exercise. Biopsy samples from the vastus lateralis were collected one week after exercise-induced muscle damage and were assessed for muscle fibre composition. There was no significant relationship (P > 0.05) between muscle fibre composition and creatine kinase activity. A significant positive correlation (P < 0.05) was observed between soreness 48 h after exercise and type II and IIb fibres, and a significant negative correlation (P < 0.05) was observed between soreness 48 h after exercise and type I muscle fibres. Significant positive correlations were observed between soreness 48 h after exercise and the fatigue index, relative average power, and relative anaerobic capacity. Our results suggest that creatine kinase activity following exercise-induced muscle damage may not be related tomuscle fibre proportions, and higher post-exercisemuscular painmay be related to a predominance of type II muscle fibres and higher anaerobic capabilities.

Original languageEnglish
Pages (from-to)257-266
Number of pages10
JournalJournal of Sports Sciences
Volume28
Issue number3
DOIs
StatePublished - Feb 2010

Keywords

  • Delayed-onset muscle soreness
  • Eccentric exercise
  • Muscle fibre type
  • Relative anaerobic capacity
  • Relative power

Fingerprint

Dive into the research topics of 'Relationship between serum creatine kinase activity following exercise-induced muscle damage and muscle fibre composition'. Together they form a unique fingerprint.

Cite this