Relationship of generalized anxiety symptoms to urinary 5-hydroxyindoleacetic acid and vanillylmandelic acid

Michael J. Garvey; Russell Noyes; Catherine Woodman; Cindy Laukes

doi:10.1016/0165-1781(94)02510-P

Relationship of generalized anxiety symptoms to urinary 5-hydroxyindoleacetic acid and vanillylmandelic acid

Michael J. Garvey
, Russell Noyes
, Catherine Woodman
, Cindy Laukes

Neural Injury Center

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 45 patients with generalized anxiety disorder. Multiple regression analysis demonstrated that the severity of several anxiety symptoms was predicted by levels of 5-HIAA and VMA. These data are consistent with the proposal that serotonin and norepinephrine may be involved in the pathophysiology of anxiety.

Original language	English
Pages (from-to)	1-5
Number of pages	5
Journal	Psychiatry Research
Volume	57
Issue number	1
DOIs	https://doi.org/10.1016/0165-1781(94)02510-P
State	Published - Jun 29 1995

Funding

Support for this study was provided by the Departmenot f VeteransA ffairs and the University of Iowa Collegeo f Medicine.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Hamilton Rating Scale for Anxiety
Norepinephrine
Serotonin

Access to Document

10.1016/0165-1781(94)02510-P

Cite this

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title = "Relationship of generalized anxiety symptoms to urinary 5-hydroxyindoleacetic acid and vanillylmandelic acid",

abstract = "Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 45 patients with generalized anxiety disorder. Multiple regression analysis demonstrated that the severity of several anxiety symptoms was predicted by levels of 5-HIAA and VMA. These data are consistent with the proposal that serotonin and norepinephrine may be involved in the pathophysiology of anxiety.",

keywords = "Hamilton Rating Scale for Anxiety, Norepinephrine, Serotonin",

author = "Garvey, \{Michael J.\} and Russell Noyes and Catherine Woodman and Cindy Laukes",

note = "Funding Information: Support for this study was provided by the Departmenot f VeteransA ffairs and the University of Iowa Collegeo f Medicine.",

year = "1995",

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doi = "10.1016/0165-1781(94)02510-P",

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T1 - Relationship of generalized anxiety symptoms to urinary 5-hydroxyindoleacetic acid and vanillylmandelic acid

AU - Garvey, Michael J.

AU - Noyes, Russell

AU - Woodman, Catherine

AU - Laukes, Cindy

N1 - Funding Information: Support for this study was provided by the Departmenot f VeteransA ffairs and the University of Iowa Collegeo f Medicine.

PY - 1995/6/29

Y1 - 1995/6/29

N2 - Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 45 patients with generalized anxiety disorder. Multiple regression analysis demonstrated that the severity of several anxiety symptoms was predicted by levels of 5-HIAA and VMA. These data are consistent with the proposal that serotonin and norepinephrine may be involved in the pathophysiology of anxiety.

AB - Urinary levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAA) and the norepinephrine metabolite vanillylmandelic acid (VMA) were measured in 45 patients with generalized anxiety disorder. Multiple regression analysis demonstrated that the severity of several anxiety symptoms was predicted by levels of 5-HIAA and VMA. These data are consistent with the proposal that serotonin and norepinephrine may be involved in the pathophysiology of anxiety.

KW - Hamilton Rating Scale for Anxiety

KW - Norepinephrine

KW - Serotonin

UR - https://www.scopus.com/pages/publications/0029002684

U2 - 10.1016/0165-1781(94)02510-P

DO - 10.1016/0165-1781(94)02510-P

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SN - 0165-1781

VL - 57

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JO - Psychiatry Research

JF - Psychiatry Research

IS - 1

ER -

Relationship of generalized anxiety symptoms to urinary 5-hydroxyindoleacetic acid and vanillylmandelic acid

Abstract

Funding

UN SDGs

Keywords

Access to Document

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