Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions

Jasmina Nikodinovic; Jennifer M. Dinges; Stephen C. Bergmeier; Mark C. McMills; Dennis L. Wright; Nigel D. Priestley

doi:10.1021/ol052739p

Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions

Jasmina Nikodinovic, Jennifer M. Dinges, Stephen C. Bergmeier, Mark C. McMills, Dennis L. Wright, Nigel D. Priestley

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18 Scopus citations

Abstract

An efficient resolution of methyl nonactate is reported by biotransformation in shake flask cultures of Rhodococcus erythropolis. The equilibrium of the reaction redox system can be manipulated by switching from aerobic to anaerobic growth, thereby generating both enantiomers of the target in excellent yield and enantiomeric purity.

Original language	English
Pages (from-to)	443-445
Number of pages	3
Journal	Organic Letters
Volume	8
Issue number	3
DOIs	https://doi.org/10.1021/ol052739p
State	Published - Feb 2 2006

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title = "Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions",

abstract = "An efficient resolution of methyl nonactate is reported by biotransformation in shake flask cultures of Rhodococcus erythropolis. The equilibrium of the reaction redox system can be manipulated by switching from aerobic to anaerobic growth, thereby generating both enantiomers of the target in excellent yield and enantiomeric purity.",

author = "Jasmina Nikodinovic and Dinges, {Jennifer M.} and Bergmeier, {Stephen C.} and McMills, {Mark C.} and Wright, {Dennis L.} and Priestley, {Nigel D.}",

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AU - Nikodinovic, Jasmina

AU - Dinges, Jennifer M.

AU - Bergmeier, Stephen C.

AU - McMills, Mark C.

AU - Wright, Dennis L.

AU - Priestley, Nigel D.

PY - 2006/2/2

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N2 - An efficient resolution of methyl nonactate is reported by biotransformation in shake flask cultures of Rhodococcus erythropolis. The equilibrium of the reaction redox system can be manipulated by switching from aerobic to anaerobic growth, thereby generating both enantiomers of the target in excellent yield and enantiomeric purity.

AB - An efficient resolution of methyl nonactate is reported by biotransformation in shake flask cultures of Rhodococcus erythropolis. The equilibrium of the reaction redox system can be manipulated by switching from aerobic to anaerobic growth, thereby generating both enantiomers of the target in excellent yield and enantiomeric purity.

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JO - Organic Letters

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Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions

Abstract

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