Resolution of methyl nonactate by Rhodococcus erythropolis under aerobic and anaerobic conditions

Jasmina Nikodinovic, Jennifer M. Dinges, Stephen C. Bergmeier, Mark C. McMills, Dennis L. Wright, Nigel D. Priestley

Research output: Contribution to journalArticlepeer-review

Abstract

An efficient resolution of methyl nonactate is reported by biotransformation in shake flask cultures of Rhodococcus erythropolis. The equilibrium of the reaction redox system can be manipulated by switching from aerobic to anaerobic growth, thereby generating both enantiomers of the target in excellent yield and enantiomeric purity.

Original languageEnglish
Pages (from-to)443-445
Number of pages3
JournalOrganic Letters
Volume8
Issue number3
DOIs
StatePublished - Feb 2 2006

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