Silica modified with polymeric amphiphilic nanoparticles as first dimension for multidimensional separation techniques

Maraíssa S. Franco; Rodrigo N. Padovan; Bruno H. Fumes; Christopher P. Palmer; Julie R. McGettrick; Fernando M. Lanças

doi:10.1016/j.chroma.2019.03.029

Silica modified with polymeric amphiphilic nanoparticles as first dimension for multidimensional separation techniques

Maraíssa S. Franco
, Rodrigo N. Padovan
, Bruno H. Fumes
, Christopher P. Palmer
, Julie R. McGettrick
, Fernando M. Lanças

Chemistry and Biochemistry

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

This paper addresses the evaluation of a new amphiphilic nanoparticle supported on silica and its application as sorbent in on-line solid phase extraction. The investigated sorbent material is a copolymer composed by [2- (Acryloyloxy) ethyl] trimethylammonium chloride (block A) and butyl acrylate (block B) prepared by reversible addition-fragmentation chain transfer. After polymerization the nanoparticles were adsorbed into silica surface by electrostatic attraction providing to the sorbent both, apolar and polar characteristics. After the fundamental studies to understand the main features of the synthesized nanoparticles supported on silica, this sorbent material was packed into an extraction column. This column was connected on line with liquid chromatography-tandem mass spectrometry and utilized for automated online determination of several analytes as Ochratoxin A, azoxystrobin, cyproconazole and difenoconazole, in wine and water samples.

Original language	English
Pages (from-to)	149-158
Number of pages	10
Journal	Journal of Chromatography A
Volume	1597
DOIs	https://doi.org/10.1016/j.chroma.2019.03.029
State	Published - Jul 19 2019

Funding

This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001. In addition, the authors are grateful to FAPESP (Grants 2017/02147-0 , 2015/15462-5 , 2015/03998-8 and 2014/07347-9 ) and to CNPq ( 307293/2014-9 ) for the financial support provided to this research and to our laboratory. Fulbright Program is also acknowledged for a fellowship to Christopher P. Palmer.

Funders	Funder number
2014/07347-9, 2015/03998-8, 2015/15462-5, 2017/02147-0
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Conselho Nacional de Desenvolvimento Científico e Tecnológico	307293/2014-9

Keywords

Amphiphilic nanoparticles
Automated extraction
Extraction column
Multidimensional separation
Ochratoxin A
On-line extraction
Pesticides
Wine

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10.1016/j.chroma.2019.03.029

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title = "Silica modified with polymeric amphiphilic nanoparticles as first dimension for multidimensional separation techniques",

abstract = "This paper addresses the evaluation of a new amphiphilic nanoparticle supported on silica and its application as sorbent in on-line solid phase extraction. The investigated sorbent material is a copolymer composed by [2- (Acryloyloxy) ethyl] trimethylammonium chloride (block A) and butyl acrylate (block B) prepared by reversible addition-fragmentation chain transfer. After polymerization the nanoparticles were adsorbed into silica surface by electrostatic attraction providing to the sorbent both, apolar and polar characteristics. After the fundamental studies to understand the main features of the synthesized nanoparticles supported on silica, this sorbent material was packed into an extraction column. This column was connected on line with liquid chromatography-tandem mass spectrometry and utilized for automated online determination of several analytes as Ochratoxin A, azoxystrobin, cyproconazole and difenoconazole, in wine and water samples.",

keywords = "Amphiphilic nanoparticles, Automated extraction, Extraction column, Multidimensional separation, Ochratoxin A, On-line extraction, Pesticides, Wine",

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AU - Franco, Maraíssa S.

AU - Padovan, Rodrigo N.

AU - Fumes, Bruno H.

AU - Palmer, Christopher P.

AU - McGettrick, Julie R.

AU - Lanças, Fernando M.

PY - 2019/7/19

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AB - This paper addresses the evaluation of a new amphiphilic nanoparticle supported on silica and its application as sorbent in on-line solid phase extraction. The investigated sorbent material is a copolymer composed by [2- (Acryloyloxy) ethyl] trimethylammonium chloride (block A) and butyl acrylate (block B) prepared by reversible addition-fragmentation chain transfer. After polymerization the nanoparticles were adsorbed into silica surface by electrostatic attraction providing to the sorbent both, apolar and polar characteristics. After the fundamental studies to understand the main features of the synthesized nanoparticles supported on silica, this sorbent material was packed into an extraction column. This column was connected on line with liquid chromatography-tandem mass spectrometry and utilized for automated online determination of several analytes as Ochratoxin A, azoxystrobin, cyproconazole and difenoconazole, in wine and water samples.

KW - Amphiphilic nanoparticles

KW - Automated extraction

KW - Extraction column

KW - Multidimensional separation

KW - Ochratoxin A

KW - On-line extraction

KW - Pesticides

KW - Wine

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JO - Journal of Chromatography A

JF - Journal of Chromatography A

ER -

Silica modified with polymeric amphiphilic nanoparticles as first dimension for multidimensional separation techniques

Abstract

Funding

Keywords

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