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Social network characteristics and cognitive function, decline, and mortality: A joint modeling approach

  • Ruijia Chen
  • , Alexander Ivan B. Posis
  • , Anna M. Pederson
  • , Jingxuan Wang
  • , Andrew K. Hirst
  • , L. Paloma Rojas-Saunero
  • , Ye Ji Kim
  • , Sebastien Haneuse
  • , Rachel Peterson
  • , Dan Mungas
  • , Jacqueline M. Torres
  • , Elizabeth Rose Mayeda
  • , Paola Gilsanz
  • , Rachel A. Whitmer
  • , Maria M. Corrada
  • , M. Maria Glymour
  • University of California at Los Angeles
  • University of California at Davis
  • Boston University
  • Harvard University
  • Kaiser Permanente
  • University of California at San Francisco
  • University of California at Irvine

Research output: Contribution to journalArticlepeer-review

Abstract

INTRODUCTION: Maintaining social relationships is challenging in advanced old age due to frequent changes in social networks. Little is known about whether social networks are associated with cognitive function, decline, and mortality in this population, or whether these associations differed by sex/gender. METHODS: Participants aged ≥90 years (n = 677; mean age = 92.9, SD = 2.2) from the multi-ethnic LifeAfter90 Study completed cognitive testing every 6 months (2019–2022). Joint models examined associations of social networks with cognitive decline and mortality, overall, and by sex/gender. RESULTS: Over 1.63 years of follow-up, 163 (24%) participants died. Baseline structural and functional social network characteristics were associated with higher executive function and verbal episodic memory, with consistent findings across sex/gender. Social networks did not predict cognitive decline or mortality. DISCUSSION: Among adults aged 90+, social networks were linked to better cognitive function but not to short-term cognitive decline or mortality.

Original languageEnglish
Article numbere71600
JournalAlzheimer's and Dementia
Volume22
Issue number7
DOIs
StatePublished - Jul 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • 90+
  • cognitive decline
  • cognitive function
  • mortality
  • social network
  • Cognitive Dysfunction/psychology
  • Social Networking
  • Humans
  • Mortality
  • Social Support
  • Male
  • Neuropsychological Tests
  • Aged, 80 and over
  • Female
  • Cognition/physiology
  • Executive Function

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