Structural origins of receptor bias

Stephen R. Sprang; Jackson Chief Elk

doi:10.1126/science.1219302

Structural origins of receptor bias

Stephen R. Sprang
, Jackson Chief Elk

Division of Biological and Biomedical Sciences

University of Montana

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Agonists can elicit pathway-specifi c conformational changes in a G protein-coupled receptor.

Original language	English
Pages (from-to)	1055-1056
Number of pages	2
Journal	Science
Volume	335
Issue number	6072
DOIs	https://doi.org/10.1126/science.1219302
State	Published - Mar 2 2012

Funding

Funder number
R56DK046371

Access to Document

10.1126/science.1219302

Cite this

@article{ba066b0012a1442a8cde9975b4987e5c,

title = "Structural origins of receptor bias",

abstract = "Agonists can elicit pathway-specifi c conformational changes in a G protein-coupled receptor.",

author = "Sprang, \{Stephen R.\} and Elk, \{Jackson Chief\}",

year = "2012",

month = mar,

day = "2",

doi = "10.1126/science.1219302",

language = "English",

volume = "335",

pages = "1055--1056",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "6072",

}

TY - JOUR

T1 - Structural origins of receptor bias

AU - Sprang, Stephen R.

AU - Elk, Jackson Chief

PY - 2012/3/2

Y1 - 2012/3/2

N2 - Agonists can elicit pathway-specifi c conformational changes in a G protein-coupled receptor.

AB - Agonists can elicit pathway-specifi c conformational changes in a G protein-coupled receptor.

UR - https://www.scopus.com/pages/publications/84857659767

U2 - 10.1126/science.1219302

DO - 10.1126/science.1219302

M3 - Short survey

C2 - 22383838

AN - SCOPUS:84857659767

SN - 0036-8075

VL - 335

SP - 1055

EP - 1056

JO - Science

JF - Science

IS - 6072

ER -

Structural origins of receptor bias

Abstract

Funding

Access to Document

Other files and links

Fingerprint

Cite this