Synthesis of fused indazole ring systems and application to nigeglanine hydrobromide

Aaron C. Sather; Orion B. Berryman; Julius Rebek

doi:10.1021/ol300303s

Synthesis of fused indazole ring systems and application to nigeglanine hydrobromide

Aaron C. Sather, Orion B. Berryman, Julius Rebek

Chemistry and Biochemistry

Scripps Research Institute

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The single-step synthesis of fused tricyclic pyridazino[1,2-a]indazolium ring systems is described. Structural details revealed by crystallography explain the unexpected reactivity. The method is applied to the gram scale synthesis of nigeglanine hydrobromide.

Original language	English
Pages (from-to)	1600-1603
Number of pages	4
Journal	Organic Letters
Volume	14
Issue number	6
DOIs	https://doi.org/10.1021/ol300303s
State	Published - Mar 16 2012

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title = "Synthesis of fused indazole ring systems and application to nigeglanine hydrobromide",

abstract = "The single-step synthesis of fused tricyclic pyridazino[1,2-a]indazolium ring systems is described. Structural details revealed by crystallography explain the unexpected reactivity. The method is applied to the gram scale synthesis of nigeglanine hydrobromide.",

author = "Sather, \{Aaron C.\} and Berryman, \{Orion B.\} and Julius Rebek",

year = "2012",

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doi = "10.1021/ol300303s",

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journal = "Organic Letters",

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T1 - Synthesis of fused indazole ring systems and application to nigeglanine hydrobromide

AU - Sather, Aaron C.

AU - Berryman, Orion B.

AU - Rebek, Julius

PY - 2012/3/16

Y1 - 2012/3/16

N2 - The single-step synthesis of fused tricyclic pyridazino[1,2-a]indazolium ring systems is described. Structural details revealed by crystallography explain the unexpected reactivity. The method is applied to the gram scale synthesis of nigeglanine hydrobromide.

AB - The single-step synthesis of fused tricyclic pyridazino[1,2-a]indazolium ring systems is described. Structural details revealed by crystallography explain the unexpected reactivity. The method is applied to the gram scale synthesis of nigeglanine hydrobromide.

UR - https://www.scopus.com/pages/publications/84858680510

U2 - 10.1021/ol300303s

DO - 10.1021/ol300303s

M3 - Article

C2 - 22385299

AN - SCOPUS:84858680510

SN - 1523-7060

VL - 14

SP - 1600

EP - 1603

JO - Organic Letters

JF - Organic Letters

IS - 6

ER -

Synthesis of fused indazole ring systems and application to nigeglanine hydrobromide

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