Twenty-one medication-free patients with generalized anxiety disorder (GAD) collected urine samples for 5-hydroxyindoleacetic acid (5-HIAA) and N-acetyl-β-glucosaminidase (NAG). Nine patients with no comorbid psychiatric diagnosis showed a significant association between 5-HIAA and NAG, r=-0.683, p=0.04. The possibility that NAG could be a marker for serotonin metabolism is discussed.
- 5-hydroxyindoleacetic acid
- Generalized anxiety disorder