The association of the serotonin metabolite, 5-HIAA, to the lysosomal enzyme N-acetyl-β-glucosaminidase

M. J. Garvey, R. Noyes, C. Woodman, C. Laukes

Research output: Contribution to journalArticlepeer-review

Abstract

Twenty-one medication-free patients with generalized anxiety disorder (GAD) collected urine samples for 5-hydroxyindoleacetic acid (5-HIAA) and N-acetyl-β-glucosaminidase (NAG). Nine patients with no comorbid psychiatric diagnosis showed a significant association between 5-HIAA and NAG, r=-0.683, p=0.04. The possibility that NAG could be a marker for serotonin metabolism is discussed.

Original languageEnglish
Pages (from-to)75-78
Number of pages4
JournalNeuropsychobiology
Volume32
Issue number2
DOIs
StatePublished - 1995

Keywords

  • 5-hydroxyindoleacetic acid
  • Generalized anxiety disorder
  • N-acetyl-β-glucosaminidase

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