The association of the serotonin metabolite, 5-HIAA, to the lysosomal enzyme N-acetyl-β-glucosaminidase

M. J. Garvey; R. Noyes; C. Woodman; C. Laukes

doi:10.1159/000119217

The association of the serotonin metabolite, 5-HIAA, to the lysosomal enzyme N-acetyl-β-glucosaminidase

M. J. Garvey, R. Noyes, C. Woodman, C. Laukes

Neural Injury Center

VA Medical Center

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Twenty-one medication-free patients with generalized anxiety disorder (GAD) collected urine samples for 5-hydroxyindoleacetic acid (5-HIAA) and N-acetyl-β-glucosaminidase (NAG). Nine patients with no comorbid psychiatric diagnosis showed a significant association between 5-HIAA and NAG, r=-0.683, p=0.04. The possibility that NAG could be a marker for serotonin metabolism is discussed.

Original language	English
Pages (from-to)	75-78
Number of pages	4
Journal	Neuropsychobiology
Volume	32
Issue number	2
DOIs	https://doi.org/10.1159/000119217
State	Published - 1995

Keywords

5-hydroxyindoleacetic acid
Generalized anxiety disorder
N-acetyl-β-glucosaminidase

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10.1159/000119217

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abstract = "Twenty-one medication-free patients with generalized anxiety disorder (GAD) collected urine samples for 5-hydroxyindoleacetic acid (5-HIAA) and N-acetyl-β-glucosaminidase (NAG). Nine patients with no comorbid psychiatric diagnosis showed a significant association between 5-HIAA and NAG, r=-0.683, p=0.04. The possibility that NAG could be a marker for serotonin metabolism is discussed.",

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AU - Noyes, R.

AU - Woodman, C.

AU - Laukes, C.

PY - 1995

Y1 - 1995

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AB - Twenty-one medication-free patients with generalized anxiety disorder (GAD) collected urine samples for 5-hydroxyindoleacetic acid (5-HIAA) and N-acetyl-β-glucosaminidase (NAG). Nine patients with no comorbid psychiatric diagnosis showed a significant association between 5-HIAA and NAG, r=-0.683, p=0.04. The possibility that NAG could be a marker for serotonin metabolism is discussed.

KW - 5-hydroxyindoleacetic acid

KW - Generalized anxiety disorder

KW - N-acetyl-β-glucosaminidase

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ER -

The association of the serotonin metabolite, 5-HIAA, to the lysosomal enzyme N-acetyl-β-glucosaminidase

Abstract

Keywords

UN SDGs

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