The berkeleyamides, amides from the acid lake fungus Penicillum rubrum

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Abstract

We previously reported several novel bioactive hybrid polyketide-terpenoid metabolites from a deep water Penicillium rubrum isolated from Berkeley Pit Lake, Butte, Montana. In this paper we report the structures of four new amides, berkeleyamides A - D (1, 4, 5, 7), isolated from extracts of this fungus. The structures of these compounds were deduced by analysis of NMR data, chemical derivatization, and comparison of their spectroscopic data to those of known compounds.

Original languageEnglish
Pages (from-to)856-860
Number of pages5
JournalJournal of Natural Products
Volume71
Issue number5
DOIs
StatePublished - May 2008

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