The membrane compression wave on the Rayleigh-Brillouin spectrum of a solution of protein in a monomer-timer equilibrium has been calculated. When the frequency of the longitudinal wave is slow compared to the monomer-dimer exchange frequency the compaction wave produces an asymmetry in the spectrum. The asymmetry is small and may be undetectable in the experimental spectra. If the frequency of the compression wave is high compared to the exchange rate then new bands will appear in the experimental spectra. The amplitude and shift of these peaks are related to the amplitude and frequency of the longitudinal wave, respectively. The bands due to the compression wave in this limit should be detectable in the experimental spectrum. Fitting of the experimental spectrum to the form calculated below will yield valuable information about the membrane compression wave.