The Innate Sense of Bacteriophages

Paul L. Bollyky; Patrick R. Secor

doi:10.1016/j.chom.2019.01.020

The Innate Sense of Bacteriophages

Paul L. Bollyky
, Patrick R. Secor

Stanford University

Research output: Contribution to journal › Short survey › peer-review

13 Scopus citations

Abstract

Perturbation of the gut microbiota is associated with inflammatory bowel disease, obesity, and even cancer. In this issue of Cell Host & Microbe, Gogokhia et al. 2019 sought to kill cancer-causing bacteria with bacteriophages. However, the bacteriophages themselves directly stimulated an immune response, which worsened inflammatory bowel disease pathogenesis.

Original language	English
Pages (from-to)	177-179
Number of pages	3
Journal	Cell Host and Microbe
Volume	25
Issue number	2
DOIs	https://doi.org/10.1016/j.chom.2019.01.020
State	Published - Feb 13 2019

Funding

We thank Laura Jennings for constructive comments on the manuscript and the NIH (R01AI138981) for supporting our phage research.

Funder number
R01AI138981

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.chom.2019.01.020

Cite this

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title = "The Innate Sense of Bacteriophages",

abstract = "Perturbation of the gut microbiota is associated with inflammatory bowel disease, obesity, and even cancer. In this issue of Cell Host \& Microbe, Gogokhia et al. 2019 sought to kill cancer-causing bacteria with bacteriophages. However, the bacteriophages themselves directly stimulated an immune response, which worsened inflammatory bowel disease pathogenesis.",

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AU - Bollyky, Paul L.

AU - Secor, Patrick R.

PY - 2019/2/13

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N2 - Perturbation of the gut microbiota is associated with inflammatory bowel disease, obesity, and even cancer. In this issue of Cell Host & Microbe, Gogokhia et al. 2019 sought to kill cancer-causing bacteria with bacteriophages. However, the bacteriophages themselves directly stimulated an immune response, which worsened inflammatory bowel disease pathogenesis.

AB - Perturbation of the gut microbiota is associated with inflammatory bowel disease, obesity, and even cancer. In this issue of Cell Host & Microbe, Gogokhia et al. 2019 sought to kill cancer-causing bacteria with bacteriophages. However, the bacteriophages themselves directly stimulated an immune response, which worsened inflammatory bowel disease pathogenesis.

UR - https://www.scopus.com/pages/publications/85060759226

U2 - 10.1016/j.chom.2019.01.020

DO - 10.1016/j.chom.2019.01.020

M3 - Short survey

C2 - 30763530

AN - SCOPUS:85060759226

SN - 1931-3128

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SP - 177

EP - 179

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 2

ER -

The Innate Sense of Bacteriophages

Abstract

Funding

UN SDGs

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