The isoxazole as a linchpin for molecules that target folded DNA conformations: Selective lateral lithiation and palladation

Xiaochun Han, Chun Li, Kevin C. Rider, Alex Blumenfeld, Brendan Twamley, N. R. Natale

Research output: Contribution to journalArticlepeer-review

Abstract

3-(10′-Halo-9′-anthracenyl)-5-methyl-4-isoxazolecarboxylic acid ethyl esters served as a useful scaffold for highly efficient lateral metalation at the C(5), and Suzuki-Fu palladium catalyzed cross coupling at the C(10′).

Original languageEnglish
Pages (from-to)7673-7677
Number of pages5
JournalTetrahedron Letters
Volume43
Issue number43
DOIs
StatePublished - Oct 21 2002

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