The outdoor air pollution and brain health workshop

Michelle L. Block, Alison Elder, Richard L. Auten, Staci D. Bilbo, Honglei Chen, Jiu Chiuan Chen, Deborah A. Cory-Slechta, Daniel Costa, David Diaz-Sanchez, David C. Dorman, Diane R. Gold, Kimberly Gray, Hueiwang Anna Jeng, Joel D. Kaufman, Michael T. Kleinman, Annette Kirshner, Cindy Lawler, David S. Miller, Srikanth S. Nadadur, Beate RitzErin O. Semmens, Leonardo H. Tonelli, Bellina Veronesi, Robert O. Wright, Rosalind J. Wright

Research output: Contribution to journalReview articlepeer-review

438 Scopus citations

Abstract

Accumulating evidence suggests that outdoor air pollution may have a significant impact on central nervous system (CNS) health and disease. To address this issue, the National Institute of Environmental Health Sciences/National Institute of Health convened a panel of research scientists that was assigned the task of identifying research gaps and priority goals essential for advancing this growing field and addressing an emerging human health concern. Here, we review recent findings that have established the effects of inhaled air pollutants in the brain, explore the potential mechanisms driving these phenomena, and discuss the recommended research priorities/approaches that were identified by the panel.

Original languageEnglish
Pages (from-to)972-984
Number of pages13
JournalNeuroToxicology
Volume33
Issue number5
DOIs
StatePublished - Oct 2012

Keywords

  • Air pollution
  • Behavior
  • Brain
  • Central nervous system
  • Epidemiology
  • Neuroinflammation
  • Neurotoxicity
  • Ozone
  • Particulate matter
  • Susceptibility

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