@article{ed62f9ada6b6460bbaa5862f7a14a816,
title = "The Pharmacogenomics Global Research Network Implementation Working Group: Global collaboration to advance pharmacogenetic implementation",
abstract = "Pharmacogenetics promises to optimize treatment-related outcomes by informing optimal drug selection and dosing based on an individual's genotype in conjunction with other important clinical factors. Despite significant evidence of genetic associations with drug response, pharmacogenetic testing has not been widely implemented into clinical practice. Among the barriers to broad implementation are limited guidance for how to successfully integrate testing into clinical workflows and limited data on outcomes with pharmacogenetic implementation in clinical practice. The Pharmacogenomics Global Research Network Implementation Working Group seeks to engage institutions globally that have implemented pharmacogenetic testing into clinical practice or are in the process or planning stages of implementing testing to collectively disseminate data on implementation strategies, metrics, and health-related outcomes with the use of genotype-guided drug therapy to ultimately help advance pharmacogenetic implementation. This paper describes the goals, structure, and initial projects of the group in addition to implementation priorities across sites and future collaborative opportunities.",
keywords = "implementation, outcomes, pharmacogenetics, strategies",
author = "Cavallari, {Larisa H.} and Hicks, {J. Kevin} and Patel, {Jai N.} and Elchynski, {Amanda L.} and Smith, {D. Max} and Bargal, {Salma A.} and Ashley Fleck and Aquilante, {Christina L.} and Killam, {Shayna R.} and Lauren Lemke and Taichi Ochi and Ramsey, {Laura B.} and Haidar, {Cyrine E.} and Teresa Ho and {El Rouby}, Nihal and Monte, {Andrew A.} and Allen, {Josiah D.} and Beitelshees, {Amber L.} and Bishop, {Jeffrey R.} and Chad Bousman and Ronald Campbell and Cicali, {Emily J.} and Cook, {Kelsey J.} and Benjamin Duong and Tsermpini, {Evangelia Eirini} and Girdwood, {Sonya Tang} and Gregornik, {David B.} and Grimsrud, {Kristin N.} and Nathan Lamb and Lee, {James C.} and Lopez, {Rocio Ortiz} and Mazhindu, {Tinashe Adrian} and Morris, {Sarah A.} and Mohamed Nagy and Jenny Nguyen and Pasternak, {Amy L.} and Natasha Petry and {Van Schaik}, {Ron H.N.} and April Schultz and Skaar, {Todd C.} and {Al Alshaykh}, Hana and Stevenson, {James M.} and Stone, {Rachael M.} and Tran, {Nam K.} and Sony Tuteja and Woodahl, {Erica L.} and Yuan, {Li Chi} and Lee, {Craig R.}",
note = "Publisher Copyright: {\textcopyright} 2024 Wolters Kluwer Health, Inc.",
year = "2024",
doi = "10.1097/FPC.0000000000000547",
language = "English",
journal = "Pharmacogenetics and Genomics",
issn = "1744-6872",
publisher = "Lippincott Williams and Wilkins Ltd.",
}