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The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus genome

  • C. H. Ahrens
  • , R. L.Q. Russell
  • , C. J. Funk
  • , J. T. Evans
  • , S. H. Harwood
  • , G. F. Rohrmann
  • Oregon State University

Research output: Contribution to journalArticlepeer-review

245 Scopus citations

Abstract

The nucleotide sequence of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus (OpMNPV) genome was completed and analyzed. It is composed of 131,990 bases with a G + C content of 55% and contains 152 putative genes of 150 nucleotides or greater. Major differences in gene content and arrangement between OpMNPV and the Autographa californica MNPV were found. These include the presence in OpMNPV of three complete iap gene homologs, two conotoxin gene homologs, two protein tyrosine phosphatase homologs, and genes encoding homologs of dUTPase and the large and small subunits of ribonucleotide reductase. Seven major intergenic repeated regions were identified. Five of these are homologous regions that are related to similar regions from other baculoviruses.

Original languageEnglish
Pages (from-to)381-399
Number of pages19
JournalVirology
Volume229
Issue number2
DOIs
StatePublished - Mar 17 1997

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